Cargando…
A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope
The ongoing threat of viral infections and the emergence of antiviral drug resistance warrants a ceaseless search for new antiviral compounds. Broadly-inhibiting compounds that act on elements shared by many viruses are promising antiviral candidates. Here, we identify a peptide derived from the cow...
Autores principales: | Luteijn, Rutger D., Praest, Patrique, Thiele, Frank, Sadasivam, Saravanan Manikam, Singethan, Katrin, Drijfhout, Jan W., Bach, Christian, de Boer, Steffen Matthijn, Lebbink, Robert J., Tao, Sha, Helfer, Markus, Bach, Nina C., Protzer, Ulrike, Costa, Ana I., Killian, J. Antoinette, Drexler, Ingo, Wiertz, Emmanuel J. H. J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7563927/ https://www.ncbi.nlm.nih.gov/pubmed/32872420 http://dx.doi.org/10.3390/cells9091989 |
Ejemplares similares
-
The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers
por: Saravanan, Manikam S., et al.
Publicado: (2019) -
Fluorescent TAP as a Platform for Virus-Induced Degradation of the Antigenic Peptide Transporter
por: Wąchalska, Magda, et al.
Publicado: (2019) -
Pathogenicity of Bovine Neonatal Pancytopenia-associated vaccine-induced alloantibodies correlates with Major Histocompatibility Complex class I expression
por: Benedictus, Lindert, et al.
Publicado: (2015) -
Phosphatidylserine receptors: Enhancers of enveloped virus entry and infection
por: Moller-Tank, Sven, et al.
Publicado: (2014) -
Differential binding of the HIV-1 envelope to phosphatidylserine receptors
por: Gu, Linlin, et al.
Publicado: (2017)