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Beta Human Papillomavirus 8E6 Attenuates Non-Homologous End Joining by Hindering DNA-PKcs Activity

Cutaneous viral infections occur in a background of near continual exposure to environmental genotoxins, like UV radiation in sunlight. Failure to repair damaged DNA is an established driver of tumorigenesis and substantial cellular resources are devoted to repairing DNA lesions. Beta-human papillom...

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Detalles Bibliográficos
Autores principales:	Hu, Changkun, Bugbee, Taylor, Gamez, Monica, Wallace, Nicholas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564021/ https://www.ncbi.nlm.nih.gov/pubmed/32825402 http://dx.doi.org/10.3390/cancers12092356

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