Nonclinical safety, tolerance and pharmacodynamics evaluation for meplazumab treating chloroquine-resistant Plasmodium falciparum

Meplazumab is an anti-CD147 humanized IgG2 antibody. The purpose of this study was to characterize the nonclinical safety, tolerance and efficacy evaluation of meplazumab treating chloroquine resistant Plasmodium falciparum. Meplazumab was well tolerated in repeat-dose toxicology studies in cynomolg...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Kun, Zhao, Yu, Zhang, Zheng, Zhang, Mengyao, Wu, Xiaodong, Bian, Huijie, Zhu, Ping, Chen, Zhinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564037/
https://www.ncbi.nlm.nih.gov/pubmed/33088688
http://dx.doi.org/10.1016/j.apsb.2020.06.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564037/
https://www.ncbi.nlm.nih.gov/pubmed/33088688
http://dx.doi.org/10.1016/j.apsb.2020.06.011

Ejemplares similares