NK-Cell-Mediated Targeting of Various Solid Tumors Using a B7-H3 Tri-Specific Killer Engager In Vitro and In Vivo

SIMPLE SUMMARY: B7-H3 costimulatory ligand has sparked tremendous interest as a target for antibody-directed therapy of solid tumors. This is attributed to high expression of B7-H3 on the surface of tumor and low expression on normal tissues. Natural killer cells are known as key effectors of the in...

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Detalles Bibliográficos
Autores principales: Vallera, Daniel A., Ferrone, Soldano, Kodal, Behiye, Hinderlie, Peter, Bendzick, Laura, Ettestad, Brianna, Hallstrom, Caroline, Zorko, Nicholas A., Rao, Arpit, Fujioka, Naomi, Ryan, Charles J., Geller, Melissa A., Miller, Jeffrey S., Felices, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564091/
https://www.ncbi.nlm.nih.gov/pubmed/32961861
http://dx.doi.org/10.3390/cancers12092659

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