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Hypercapnia promotes microglial pyroptosis via inhibiting mitophagy in hypoxemic adult rats

BACKGROUND: Hypoxemia is a typical symptom of acute respiratory distress syndrome. To avoid pulmonary morbidity, low tidal volume ventilation is often applied. The ventilation strategy will certainly cause hypercapnia. This study aimed to explore whether hypercapnia would promote microglial pyroptos...

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Detalles Bibliográficos
Autores principales:	Ding, Hong‐guang, Li, Ya, Li, Xu‐sheng, Liu, Xin‐qiang, Wang, Kang‐rong, Wen, Miao‐yun, Jiang, Wen‐qiang, Zeng, Hong‐ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564198/ https://www.ncbi.nlm.nih.gov/pubmed/32666671 http://dx.doi.org/10.1111/cns.13435

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