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Juniperonic Acid Biosynthesis is Essential in Caenorhabditis elegans Lacking Δ6 Desaturase (fat-3) and Generates New ω-3 Endocannabinoids

In eukaryotes, the C20:4 polyunsaturated fatty acid arachidonic acid (AA) plays important roles as a phospholipid component, signaling molecule and precursor of the endocannabinoid-prostanoid axis. Accordingly, the absence of AA causes detrimental effects. Here, compensatory mechanisms involved in A...

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Detalles Bibliográficos
Autores principales: Guha, Sujay, Calarco, Serafina, Gachet, M. Salomé, Gertsch, Jürg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564282/
https://www.ncbi.nlm.nih.gov/pubmed/32961767
http://dx.doi.org/10.3390/cells9092127

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