Cargando…

The Diagnostic Accuracy of Mutant KRAS Detection from Pancreatic Secretions for the Diagnosis of Pancreatic Cancer: A Meta-Analysis

This meta-analysis aims to identify the diagnostic accuracy of mutations in the Kirsten Rat Sarcoma (KRAS) oncogene in the diagnosis of pancreatic ductal adenocarcinoma (PDAC). The survival of PDAC remains poor often due to the fact that disease is advanced at diagnosis. We analysed 22 studies, with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Patel, Nikhil, Petrinic, Tatjana, Silva, Michael, Soonawalla, Zahir, Reddy, Srikanth, Gordon-Weeks, Alex
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564395/ https://www.ncbi.nlm.nih.gov/pubmed/32825312 http://dx.doi.org/10.3390/cancers12092353

Ejemplares similares

A meta-analysis of CXCL12 expression for cancer prognosis
por: Samarendra, Harsh, et al.
Publicado: (2017)

Targeting Mutant KRAS in Pancreatic Cancer: Futile or Promising?
por: Nollmann, Friederike Inga, et al.
Publicado: (2020)

KRAS Mutant Pancreatic Cancer: No Lone Path to an Effective Treatment
por: Zeitouni, Daniel, et al.
Publicado: (2016)

The safety of telemedicine clinics as an alternative to in-person preoperative assessment for elective laparoscopic cholecystectomy in patients with benign gallbladder disease: a retrospective cohort study
por: Urbonas, Tomas, et al.
Publicado: (2023)

Metabolic profiling of induced acute pancreatitis and pancreatic cancer progression in a mutant Kras mouse model
por: Carneiro, Tatiana J., et al.
Publicado: (2022)

Thioredoxin system-mediated regulation of mutant Kras associated pancreatic neoplasia and cancer
por: Schultz, Michelle A., et al.
Publicado: (2017)

Mutant KRAS drives metabolic reprogramming and autophagic flux in premalignant pancreatic cells
por: Suzuki, Tatsunori, et al.
Publicado: (2021)

Mutant KRAS and GNAS DNA Concentrations in Secretin-Stimulated Pancreatic Fluid Collected from the Pancreatic Duct and the Duodenal Lumen
por: Sadakari, Yoshihiko, et al.
Publicado: (2014)

Targeting KRAS in Pancreatic Cancer
por: Cowzer, Darren, et al.
Publicado: (2022)

Autologous blood transfusion reduces the requirement for perioperative allogenic blood transfusion in patients undergoing major hepatopancreatobiliary surgery: a retrospective cohort study
por: Lakha, Adil S., et al.
Publicado: (2023)

Synergistic blocking of RAS downstream signaling and epigenetic pathway in KRAS mutant pancreatic cancer
por: Zhang, Xiaofei, et al.
Publicado: (2022)

Endoscopic ultrasound-guided drainage of pancreatic walled-off necrosis using self-expanding metal stents without fluoroscopy
por: Braden, Barbara, et al.
Publicado: (2018)

Predicting Early Disease Recurrence of Pancreatic Cancer following Surgery: Determining the Role of NUDT15 as a Prognostic Biomarker
por: Hughes, Daniel Llwyd, et al.
Publicado: (2022)

KRAS mutant allele-specific expression knockdown in pancreatic cancer model with systemically delivered bi-shRNA KRAS lipoplex
por: Rao, Donald D., et al.
Publicado: (2018)

The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer
por: Diehl, J. Nathaniel, et al.
Publicado: (2021)

Pancreatic cyst fluid harboring a KRAS mutation
por: Al-Turkmani, M. Rabie, et al.
Publicado: (2019)

The value of KRAS mutation testing with CEA for the diagnosis of pancreatic mucinous cysts
por: Kadayifci, Abdurrahman, et al.
Publicado: (2016)

Spiclomazine displays a preferential anti-tumor activity in mutant KRas-driven pancreatic cancer
por: Guo, Xiaoyu, et al.
Publicado: (2018)

Role of GRP78 inhibiting artesunate-induced ferroptosis in KRAS mutant pancreatic cancer cells
por: Wang, Kang, et al.
Publicado: (2019)

KRAS mutant–driven SUMOylation controls extracellular vesicle transmission to trigger lymphangiogenesis in pancreatic cancer
por: Luo, Yuming, et al.
Publicado: (2022)

Oncogenic KRAS signalling in pancreatic cancer
por: Eser, S, et al.
Publicado: (2014)

Pancreatic stellate cells activated by mutant KRAS-mediated PAI-1 upregulation foster pancreatic cancer progression via IL-8
por: Wang, Hao-Chen, et al.
Publicado: (2019)

Diagnosis of pancreatic adenocarcinoma by polymerase chain reaction from pancreatic secretions.
por: Trümper, L. H., et al.
Publicado: (1994)

Induction of pancreatic neoplasia in the KRAS/TP53 Oncopig
por: Mondal, Pinaki, et al.
Publicado: (2023)

Activated Regulatory T-Cells, Dysfunctional and Senescent T-Cells Hinder the Immunity in Pancreatic Cancer
por: Sivakumar, Shivan, et al.
Publicado: (2021)

Differential diagnosis between chronic pancreatitis and pancreatic cancer: value of the detection of KRAS2 mutations in circulating DNA
por: Maire, F, et al.
Publicado: (2002)

Dysregulation of KRAS signaling in pancreatic cancer is not associated with KRAS mutations and outcome
por: Lemstrova, Radmila, et al.
Publicado: (2017)

Rapid acceleration of KRAS-mutant pancreatic carcinogenesis via remodeling of tumor immune microenvironment by PPARδ
por: Liu, Yi, et al.
Publicado: (2022)

Mutant KRAS Mediates circARFGEF2 Biogenesis to Promote Lymphatic Metastasis of Pancreatic Ductal Adenocarcinoma
por: Kong, Yao, et al.
Publicado: (2023)

STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancer
por: D’Amico, Stephen, et al.
Publicado: (2023)

KRAS as a Key Oncogene in the Clinical Precision Diagnosis and Treatment of Pancreatic Cancer
por: Dai, Manxiong, et al.
Publicado: (2022)

KRAS above and beyond – EGFR in pancreatic cancer
por: Siveke, Jens T., et al.
Publicado: (2012)

Beyond Kras: MYC Rules in Pancreatic Cancer
por: Korc, Murray
Publicado: (2018)

Zebrafish model of KRAS-initiated pancreatic cancer
por: Park, Joon Tae, et al.
Publicado: (2018)

Diagnostic accuracy of cyst fluid amphiregulin in pancreatic cysts
por: Tun, May T, et al.
Publicado: (2012)

Pancreatic duct ligation reduces premalignant pancreatic lesions in a Kras model of pancreatic adenocarcinoma in mice
por: Cáceres, Marta, et al.
Publicado: (2020)

The prognostic role of desmoplastic stroma in pancreatic ductal adenocarcinoma
por: Wang, Lai Mun, et al.
Publicado: (2015)

Experiences and supportive care needs of UK patients with pancreatic cancer: a cross-sectional questionnaire survey
por: Watson, Eila K, et al.
Publicado: (2019)

A MEK/PI3K/HDAC inhibitor combination therapy for KRAS mutant pancreatic cancer cells
por: Ischenko, Irene, et al.
Publicado: (2015)

A recombinant chimeric protein specifically induces mutant KRAS degradation and potently inhibits pancreatic tumor growth
por: Pan, Ting, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_svgd856cljlvaikpt2l8eegf8p