Synthesis of Antibacterial Gelatin/Sodium Alginate Sponges and Their Antibacterial Activity

In the present study, sponges with the antibiotic tetracycline hydrochloride (TCH) loaded into alginate incorporated with gelatin (G/SA) were fabricated. The G/SA sponges were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and thermogravimetric (T...

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Detalles Bibliográficos
Autores principales: Wen, Yanyi, Yu, Bing, Zhu, Zhongjie, Yang, Zhuoran, Shao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564498/
https://www.ncbi.nlm.nih.gov/pubmed/32858972
http://dx.doi.org/10.3390/polym12091926
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author Wen, Yanyi
Yu, Bing
Zhu, Zhongjie
Yang, Zhuoran
Shao, Wei
author_facet Wen, Yanyi
Yu, Bing
Zhu, Zhongjie
Yang, Zhuoran
Shao, Wei
author_sort Wen, Yanyi
collection PubMed
description In the present study, sponges with the antibiotic tetracycline hydrochloride (TCH) loaded into alginate incorporated with gelatin (G/SA) were fabricated. The G/SA sponges were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and thermogravimetric (TG) analysis. G/SA sponges show a three-dimensional network structure with high porosity. An excellent swelling behavior and a controlled TCH release performance are observed from G/SA sponges. Moreover, they exhibit good antibacterial activity against both Gram-positive and Gram-negative bacteria.
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spelling pubmed-75644982020-10-27 Synthesis of Antibacterial Gelatin/Sodium Alginate Sponges and Their Antibacterial Activity Wen, Yanyi Yu, Bing Zhu, Zhongjie Yang, Zhuoran Shao, Wei Polymers (Basel) Article In the present study, sponges with the antibiotic tetracycline hydrochloride (TCH) loaded into alginate incorporated with gelatin (G/SA) were fabricated. The G/SA sponges were characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR) and thermogravimetric (TG) analysis. G/SA sponges show a three-dimensional network structure with high porosity. An excellent swelling behavior and a controlled TCH release performance are observed from G/SA sponges. Moreover, they exhibit good antibacterial activity against both Gram-positive and Gram-negative bacteria. MDPI 2020-08-26 /pmc/articles/PMC7564498/ /pubmed/32858972 http://dx.doi.org/10.3390/polym12091926 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wen, Yanyi
Yu, Bing
Zhu, Zhongjie
Yang, Zhuoran
Shao, Wei
Synthesis of Antibacterial Gelatin/Sodium Alginate Sponges and Their Antibacterial Activity
title Synthesis of Antibacterial Gelatin/Sodium Alginate Sponges and Their Antibacterial Activity
title_full Synthesis of Antibacterial Gelatin/Sodium Alginate Sponges and Their Antibacterial Activity
title_fullStr Synthesis of Antibacterial Gelatin/Sodium Alginate Sponges and Their Antibacterial Activity
title_full_unstemmed Synthesis of Antibacterial Gelatin/Sodium Alginate Sponges and Their Antibacterial Activity
title_short Synthesis of Antibacterial Gelatin/Sodium Alginate Sponges and Their Antibacterial Activity
title_sort synthesis of antibacterial gelatin/sodium alginate sponges and their antibacterial activity
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564498/
https://www.ncbi.nlm.nih.gov/pubmed/32858972
http://dx.doi.org/10.3390/polym12091926
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