Mucosal Vaccination with UV-Inactivated Chlamydia suis in Pre-Exposed Outbred Pigs Decreases Pathogen Load and Induces CD4 T-Cell Maturation into IFN-γ(+) Effector Memory Cells

Chlamydia trachomatis (Ct) infections are the most frequent bacterial sexually transmitted disease, and they can lead to ectopic pregnancy and infertility. Despite these detrimental long-term sequelae, a vaccine is not available. Success in preclinical animal studies is essential for vaccines to mov...

Descripción completa

Detalles Bibliográficos
Autores principales: Amaral, Amanda F., Rahman, Khondaker S., Kick, Andrew R., Cortes, Lizette M., Robertson, James, Kaltenboeck, Bernhard, Gerdts, Volker, O’Connell, Catherine M., Poston, Taylor B., Zheng, Xiaojing, Liu, Chuwen, Omesi, Sam Y., Darville, Toni, Käser, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564508/
https://www.ncbi.nlm.nih.gov/pubmed/32630694
http://dx.doi.org/10.3390/vaccines8030353

Ejemplares similares

Ejemplares similares