Cargando…

Use of Biomarkers in Ongoing Research Protocols on Alzheimer’s Disease

The present study aimed to describe and discuss the state of the art of biomarker use in ongoing Alzheimer’s disease (AD) research. A review of 222 ongoing phase 1, 2, 3, and 4 protocols registered in the clinicaltrials.gov database was performed. All the trials (i) enrolling subjects with clinical...

Descripción completa

Detalles Bibliográficos
Autores principales:	Canevelli, Marco, Remoli, Giulia, Bacigalupo, Ilaria, Valletta, Martina, Toccaceli Blasi, Marco, Sciancalepore, Francesco, Bruno, Giuseppe, Cesari, Matteo, Vanacore, Nicola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564515/ https://www.ncbi.nlm.nih.gov/pubmed/32722106 http://dx.doi.org/10.3390/jpm10030068

Ejemplares similares

Methodological Issues in the Clinical Validation of Biomarkers for Alzheimer’s Disease: The Paradigmatic Example of CSF
por: Canevelli, Marco, et al.
Publicado: (2019)

Biomarkers and phenotypic expression in Alzheimer’s disease: exploring the contribution of frailty in the Alzheimer’s Disease Neuroimaging Initiative
por: Canevelli, Marco, et al.
Publicado: (2020)

Anticancer drugs repurposed for Alzheimer’s disease: a systematic review
por: Ancidoni, Antonio, et al.
Publicado: (2021)

A nationwide survey of Italian Centers for Cognitive Disorders and Dementia on the provision of care for international migrants
por: Canevelli, Marco, et al.
Publicado: (2022)

Safety and Efficacy of Monoclonal Antibodies for Alzheimer’s Disease: A Systematic Review and Meta-Analysis of Published and Unpublished Clinical Trials
por: Lacorte, Eleonora, et al.
Publicado: (2022)

COVID-19 and dementia: Recommendations from the Italian dementia national plan working group
por: Canevelli, Marco, et al.
Publicado: (2021)

The Italian national survey on COVID-19 in nursing homes during the first wave of the pandemic
por: Lombardo, Flavia, et al.
Publicado: (2021)

Providing Simultaneous COVID-19–sensitive and Dementia-Sensitive Care as We Transition from Crisis Care to Ongoing Care
por: Canevelli, Marco, et al.
Publicado: (2020)

The Pipeline of Therapeutics Testing During the Emergency Phase of the COVID-19 Outbreak
por: Canevelli, Marco, et al.
Publicado: (2020)

Mild Cognitive Impairment in the Migrant Population Living in Europe: An Epidemiological Estimation of the Phenomenon
por: Canevelli, Marco, et al.
Publicado: (2020)

Spontaneous Reversion of Clinical Conditions Measuring the Risk Profile of the Individual: From Frailty to Mild Cognitive Impairment
por: Canevelli, Marco, et al.
Publicado: (2017)

An Estimate of Attributable Cases of Alzheimer Disease and Vascular Dementia due to Modifiable Risk Factors: The Impact of Primary Prevention in Europe and in Italy
por: Mayer, Flavia, et al.
Publicado: (2018)

A Systematic Review and Meta-Analysis on the Prevalence of Dementia in Europe: Estimates from the Highest-Quality Studies Adopting the DSM IV Diagnostic Criteria
por: Bacigalupo, Ilaria, et al.
Publicado: (2018)

The Italian national survey on Coronavirus disease 2019 epidemic spread in nursing homes
por: Lombardo, Flavia L., et al.
Publicado: (2021)

Integrated care pathways on dementia in Italy: a survey testing the compliance with a national guidance
por: Gervasi, Giuseppe, et al.
Publicado: (2019)

A National Survey of Centers for Cognitive Disorders and Dementias in Italy
por: Canevelli, Marco, et al.
Publicado: (2021)

External Validity of Randomized Controlled Trials on Alzheimer’s Disease: The Biases of Frailty and Biological Aging
por: Canevelli, Marco, et al.
Publicado: (2017)

Case Identification and Characterization of Migrants with Dementia in the Lazio Region Using Health Administrative Data
por: Cascini, Silvia, et al.
Publicado: (2023)

Horse-Racing Effect and Clinical Trials in Older Persons
por: Cesari, Matteo, et al.
Publicado: (2014)

Nutrition and Dementia: Evidence for Preventive Approaches?
por: Canevelli, Marco, et al.
Publicado: (2016)

Adverse Events in Italian Nursing Homes During the COVID-19 Epidemic: A National Survey
por: Lombardo, Flavia L., et al.
Publicado: (2020)

Sundowning in Dementia: Clinical Relevance, Pathophysiological Determinants, and Therapeutic Approaches
por: Canevelli, Marco, et al.
Publicado: (2016)

Editorial: Dementia, Frailty and Aging
por: Lim, Wee-Shiong, et al.
Publicado: (2018)

Dementia among migrants and ethnic minorities in Italy: rationale and study protocol of the ImmiDem project
por: Canevelli, Marco, et al.
Publicado: (2020)

A Systematic Review of the Microbiome in Children With Neurodevelopmental Disorders
por: Lacorte, Eleonora, et al.
Publicado: (2019)

Computer-Based Cognitive Training in Children with Primary Brain Tumours: A Systematic Review
por: Sciancalepore, Francesco, et al.
Publicado: (2022)

Frailty as a Predictor of Cognitive Disorders: A Systematic Review and Meta-Analysis
por: Borges, Marcus Kiiti, et al.
Publicado: (2019)

An ontology-based approach for modelling and querying Alzheimer’s disease data
por: Taglino, Francesco, et al.
Publicado: (2023)

Promoting the Assessment of Frailty in the Clinical Approach to Cognitive Disorders
por: Canevelli, Marco, et al.
Publicado: (2017)

On Schrödinger’s Cat and Evaluation of Trials Disrupted by the Covid19 Pandemic: A Critical Appraisal
por: Cesari, Matteo, et al.
Publicado: (2021)

Prevalence and clinical correlates of dementia among COVID‐19‐related deaths in Italy
por: Canevelli, Marco, et al.
Publicado: (2020)

A Frailty Index based on clinical data to quantify mortality risk in dogs
por: Banzato, Tommaso, et al.
Publicado: (2019)

The Genetic Diagnosis of Ultrarare DEEs: An Ongoing Challenge
por: Musante, Luciana, et al.
Publicado: (2022)

The Impact of Frailty on the Risk of Conversion from Mild Cognitive Impairment to Alzheimer’s Disease: Evidences from a 5-Year Observational Study
por: Trebbastoni, Alessandro, et al.
Publicado: (2017)

The Management of Ruptured Abdominal Aortic Aneurysms: An Ongoing Challenge
por: Troisi, Nicola, et al.
Publicado: (2023)

Neurophysiological and clinical biomarkers of secondary progressive multiple sclerosis: A cross-sectional study
por: Tartaglia, Matteo, et al.
Publicado: (2023)

Sex differences in clinical phenotype and transitions of care among individuals dying of COVID-19 in Italy
por: Raparelli, Valeria, et al.
Publicado: (2020)

Immune checkpoint inhibitor induced nephrotoxicity: An ongoing challenge
por: Catalano, Martina, et al.
Publicado: (2022)

Prevalence of amyotrophic lateral sclerosis in Latium region, Italy
por: Puopolo, Maria, et al.
Publicado: (2021)

The Chemical Synthesis of Tetrodoxin: An Ongoing Quest
por: Chau, Jaclyn, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_tp9dm6cs8e51pcrunqr3mgmt3o