5-aza-2′-Deoxycytidine Induces a RIG-I-Related Innate Immune Response by Modulating Mitochondria Stress in Neuroblastoma

Background: Neuroblastoma (NB) is one of the most common malignant solid tumors to occur in children, characterized by a wide range of genetic and epigenetic aberrations. We studied whether modifications of the latter with a 5-aza-2′-deoxycytidine (decitabine, Dac) DNA methyltransferase inhibitor ca...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Hung-Yu, Chuang, Jiin-Haur, Wang, Pei-Wen, Lin, Tsu-Kung, Wu, Min-Tsui, Hsu, Wen-Ming, Chuang, Hui-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564572/
https://www.ncbi.nlm.nih.gov/pubmed/32824929
http://dx.doi.org/10.3390/cells9091920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564572/
https://www.ncbi.nlm.nih.gov/pubmed/32824929
http://dx.doi.org/10.3390/cells9091920

Ejemplares similares