Subcellular Localization and Mitotic Interactome Analyses Identify SIRT4 as a Centrosomally Localized and Microtubule Associated Protein

The stress-inducible and senescence-associated tumor suppressor SIRT4, a member of the family of mitochondrial sirtuins (SIRT3, SIRT4, and SIRT5), regulates bioenergetics and metabolism via NAD(+)-dependent enzymatic activities. Next to the known mitochondrial location, we found that a fraction of e...

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Detalles Bibliográficos
Autores principales: Bergmann, Laura, Lang, Alexander, Bross, Christoph, Altinoluk-Hambüchen, Simone, Fey, Iris, Overbeck, Nina, Stefanski, Anja, Wiek, Constanze, Kefalas, Andreas, Verhülsdonk, Patrick, Mielke, Christian, Sohn, Dennis, Stühler, Kai, Hanenberg, Helmut, Jänicke, Reiner U., Scheller, Jürgen, Reichert, Andreas S., Ahmadian, Mohammad Reza, Piekorz, Roland P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564595/
https://www.ncbi.nlm.nih.gov/pubmed/32846968
http://dx.doi.org/10.3390/cells9091950

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