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Gut Microbial Changes in Diabetic db/db Mice and Recovery of Microbial Diversity upon Pirfenidone Treatment

The leptin receptor-deficient db/db mouse model is an accepted in vivo model to study obesity, type 2 diabetes, and diabetic kidney disease. Healthy gastrointestinal (GI) microbiota has been linked to weight loss, improved glycemic control, and physiological benefits. We investigated the effect of v...

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Detalles Bibliográficos
Autores principales: Singh, Harinder, Miyamoto, Satoshi, Darshi, Manjula, Torralba, Manolito G., Kwon, Keehwan, Sharma, Kumar, Pieper, Rembert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564638/
https://www.ncbi.nlm.nih.gov/pubmed/32899353
http://dx.doi.org/10.3390/microorganisms8091347