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Integrating Phenotypic Search and Phosphoproteomic Profiling of Active Kinases for Optimization of Drug Mixtures for RCC Treatment

SIMPLE SUMMARY: Renal cell carcinoma (RCC) cancer is among the ten most common malignancies, and frequently presents as metastatic disease (mRCC). For these patients, systemic treatment is in order, but mRCC is often highly heterogeneous, and resistant to conventional therapies, or acquires resistan...

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Detalles Bibliográficos
Autores principales: van Beijnum, Judy R., Weiss, Andrea, Berndsen, Robert H., Wong, Tse J., Reckman, Louise C., Piersma, Sander R., Zoetemelk, Marloes, de Haas, Richard, Dormond, Olivier, Bex, Axel, Henneman, Alexander A., Jimenez, Connie R., Griffioen, Arjan W., Nowak-Sliwinska, Patrycja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564658/
https://www.ncbi.nlm.nih.gov/pubmed/32967224
http://dx.doi.org/10.3390/cancers12092697

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