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Integrating Phenotypic Search and Phosphoproteomic Profiling of Active Kinases for Optimization of Drug Mixtures for RCC Treatment
SIMPLE SUMMARY: Renal cell carcinoma (RCC) cancer is among the ten most common malignancies, and frequently presents as metastatic disease (mRCC). For these patients, systemic treatment is in order, but mRCC is often highly heterogeneous, and resistant to conventional therapies, or acquires resistan...
Autores principales: | van Beijnum, Judy R., Weiss, Andrea, Berndsen, Robert H., Wong, Tse J., Reckman, Louise C., Piersma, Sander R., Zoetemelk, Marloes, de Haas, Richard, Dormond, Olivier, Bex, Axel, Henneman, Alexander A., Jimenez, Connie R., Griffioen, Arjan W., Nowak-Sliwinska, Patrycja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564658/ https://www.ncbi.nlm.nih.gov/pubmed/32967224 http://dx.doi.org/10.3390/cancers12092697 |
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