Cargando…

Safety and Efficacy Evaluation of Recombinant Marek’s Disease Virus with REV-LTR

Recently, chickens vaccinated with the CVI988/Rispens vaccine showed increased tumor incidence. Moreover, many strains of Marek’s disease virus (MDV) that were naturally integrated with the long terminal repeat (LTR) of the avian reticuloendotheliosis virus (REV) have been isolated, which means it i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Song, Cuiping, Yang, Yang, Hu, Jing, Yu, Shengqing, Sun, Yingjie, Qiu, Xvsheng, Tan, Lei, Meng, Chunchun, Liao, Ying, Liu, Weiwei, Ding, Chan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564749/ https://www.ncbi.nlm.nih.gov/pubmed/32698460 http://dx.doi.org/10.3390/vaccines8030399

Ejemplares similares

Newcastle Disease virus infection activates PI3K/Akt/mTOR and p38 MAPK/Mnk1 pathways to benefit viral mRNA translation via interaction of the viral NP protein and host eIF4E
por: Zhan, Yuan, et al.
Publicado: (2020)

Chicken RNA-binding protein T-cell internal antigen-1 contributes to stress granule formation in chicken cells and tissues
por: Sun, Yingjie, et al.
Publicado: (2018)

A Recombinant La Sota Vaccine Strain Expressing Multiple Epitopes of Infectious Bronchitis Virus (IBV) Protects Specific Pathogen-Free (SPF) Chickens against IBV and NDV Challenges
por: Tan, Lei, et al.
Publicado: (2019)

Genome-Wide Analysis of Alternative Splicing during Host-Virus Interactions in Chicken
por: Liu, Weiwei, et al.
Publicado: (2021)

Vitamin E Supplementation Ameliorates Newcastle Disease Virus-Induced Oxidative Stress and Alleviates Tissue Damage in the Brains of Chickens
por: Rehman, Zaib Ur, et al.
Publicado: (2018)

Caspase-Dependent Cleavage of DDX21 Suppresses Host Innate Immunity
por: Wu, Wei, et al.
Publicado: (2021)

Comparison of the protective antigen variabilities of prevalent Newcastle disease viruses in response to homologous/heterologous genotype vaccines
por: Li, Yonghua, et al.
Publicado: (2021)

Deep Sequencing-Based Transcriptome Profiling Reveals Avian Interferon-Stimulated Genes and Provides Comprehensive Insight into Newcastle Disease Virus-Induced Host Responses
por: Liu, Weiwei, et al.
Publicado: (2018)

Exosomes Carry microRNAs into Neighboring Cells to Promote Diffusive Infection of Newcastle Disease Virus
por: Zhou, Changluan, et al.
Publicado: (2019)

Upregulation of DUSP6 impairs infectious bronchitis virus replication by negatively regulating ERK pathway and promoting apoptosis
por: Wang, Huan, et al.
Publicado: (2021)

In Vitro and In Vivo Metabolomic Profiling after Infection with Virulent Newcastle Disease Virus
por: Liu, Panrao, et al.
Publicado: (2019)

Characterization of the Protective Efficacy Against QX Strain of a Recombinant Infectious Bronchitis Virus With H120 Backbone and QX Spike Gene
por: Weng, Wenlian, et al.
Publicado: (2022)

Attenuation of a recombinant Marek's disease virus lacking the meq oncogene and evaluation on its immune efficacy against Marek's disease virus
por: Sun, Peng, et al.
Publicado: (2020)

Phylogenetic, antigenic and biological characterization of pigeon paramyxovirus type 1 circulating in China
por: Qiu, Xusheng, et al.
Publicado: (2017)

SLC1A3 facilitates Newcastle disease virus replication by regulating glutamine catabolism
por: Liu, Panrao, et al.
Publicado: (2022)

Newcastle disease virus employs macropinocytosis and Rab5a-dependent intracellular trafficking to infect DF-1 cells
por: Tan, Lei, et al.
Publicado: (2016)

Infectious bronchitis virus entry mainly depends on clathrin mediated endocytosis and requires classical endosomal/lysosomal system
por: Wang, Huan, et al.
Publicado: (2019)

eIF2α-CHOP-BCl-2/JNK and IRE1α-XBP1/JNK signaling promote apoptosis and inflammation and support the proliferation of Newcastle disease virus
por: Li, Yanrong, et al.
Publicado: (2019)

Development of Strand-Specific Real-Time RT-PCR to Distinguish Viral RNAs during Newcastle Disease Virus Infection
por: Qiu, Xusheng, et al.
Publicado: (2014)

Newcastle Disease Virus V Protein Targets Phosphorylated STAT1 to Block IFN-I Signaling
por: Qiu, Xusheng, et al.
Publicado: (2016)

Newcastle disease virus induces G(0)/G(1) cell cycle arrest in asynchronously growing cells
por: Wang, Yan, et al.
Publicado: (2018)

Development of a Recombinant Thermostable Newcastle Disease Virus (NDV) Vaccine Express Infectious Bronchitis Virus (IBV) Multiple Epitopes for Protecting against IBV and NDV Challenges
por: Tan, Lei, et al.
Publicado: (2020)

Recombinant Marek’s disease virus type 1 provides full protection against very virulent Marek’s and infectious bursal disease viruses in chickens
por: Li, Kai, et al.
Publicado: (2016)

Inhibition of anti-viral stress granule formation by coronavirus endoribonuclease nsp15 ensures efficient virus replication
por: Gao, Bo, et al.
Publicado: (2021)

Co-Infection with Marek’s Disease Virus and Reticuloendotheliosis Virus Increases Illness Severity and Reduces Marek’s Disease Vaccine Efficacy
por: Sun, Guo-Rong, et al.
Publicado: (2017)

Newcastle Disease Virus Induced Pathologies Severely Affect the Exocrine and Endocrine Functions of the Pancreas in Chickens
por: Rehman, Zaib Ur, et al.
Publicado: (2021)

Variation in proviral content among human genomes mediated by LTR recombination
por: Thomas, Jainy, et al.
Publicado: (2018)

Activation of the PKR/eIF2α signaling cascade inhibits replication of Newcastle disease virus
por: Zhang, Shilei, et al.
Publicado: (2014)

Newcastle-disease-virus-induced ferroptosis through nutrient deprivation and ferritinophagy in tumor cells
por: Kan, Xianjin, et al.
Publicado: (2021)

REV1 and polymerase ζ facilitate homologous recombination repair
por: Sharma, Shilpy, et al.
Publicado: (2012)

The conservation and signatures of lincRNAs in Marek’s disease of chicken
por: He, Yanghua, et al.
Publicado: (2015)

Coronavirus Infection and Cholesterol Metabolism
por: Dai, Jun, et al.
Publicado: (2022)

Becoming a Selfish Clan: Recombination Associated to Reverse-Transcription in LTR Retrotransposons
por: Drost, Hajk-Georg, et al.
Publicado: (2019)

Single-Cell Transcriptome Atlas of Newcastle Disease Virus in Chickens Both In Vitro and In Vivo
por: Liu, Weiwei, et al.
Publicado: (2023)

Newcastle disease virus induces testicular damage and disrupts steroidogenesis in specific pathogen free roosters
por: Rehman, Zaib Ur, et al.
Publicado: (2020)

LTR_FINDER: an efficient tool for the prediction of full-length LTR retrotransposons
por: Xu, Zhao, et al.
Publicado: (2007)

The Role of Marek’s Disease Virus UL12 and UL29 in DNA Recombination and the Virus Lifecycle
por: Previdelli, Renato L., et al.
Publicado: (2019)

Phenotypic Characterization of Recombinant Marek’s Disease Virus in Live Birds Validates Polymorphisms Associated with Virulence
por: Kim, Taejoong, et al.
Publicado: (2023)

Microsatellite instability in Marek’s Disease Virus infected primary chicken embryo fibroblasts
por: Zhou, Zhenlei, et al.
Publicado: (2012)

The Meq oncoprotein of Marek's disease virus interacts with p53 and inhibits its transcriptional and apoptotic activities
por: Deng, Xufang, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_26q0ar4bbnup37baac78391kch