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AMPK-Dependent Mechanisms but Not Hypothalamic Lipid Signaling Mediates GH-Secretory Responses to GHRH and Ghrelin
GH (growth hormone) secretion/action is modulated by alterations in energy homeostasis, such as malnutrition and obesity. Recent data have uncovered the mechanism by which hypothalamic neurons sense nutrient bioavailability, with a relevant contribution of AMPK (AMP-activated protein kinase) and mTO...
Autores principales: | Vázquez, María J., Novelle, Marta G., Rodríguez-Pacheco, Francisca, Lage, Ricardo, Varela, Luis, López, Miguel, Pinilla, Leonor, Tena-Sempere, Manuel, Diéguez, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564832/ https://www.ncbi.nlm.nih.gov/pubmed/32839401 http://dx.doi.org/10.3390/cells9091940 |
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