Hormonal Receptor Status Determines Prognostic Significance of FGFR2 in Invasive Breast Carcinoma

SIMPLE SUMMARY: FGFR2-ER-PR crosstalk leads to hormone-independent progression of breast cancer. In vitro, FGFR2 stimulates PR transcriptional activity and mediates resistance to anti-ER therapies. The postulated poor prognostic effect of FGFR2 overexpression has not been confirmed at clinical level...

Descripción completa

Detalles Bibliográficos
Autores principales: Braun, Marcin, Piasecka, Dominika, Tomasik, Bartlomiej, Mieczkowski, Kamil, Stawiski, Konrad, Zielinska, Aleksandra, Kopczynski, Janusz, Nejc, Dariusz, Kordek, Radzislaw, Sadej, Rafal, Romanska, Hanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564845/
https://www.ncbi.nlm.nih.gov/pubmed/32971804
http://dx.doi.org/10.3390/cancers12092713

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564845/
https://www.ncbi.nlm.nih.gov/pubmed/32971804
http://dx.doi.org/10.3390/cancers12092713

Ejemplares similares