Cargando…

Hormonal Receptor Status Determines Prognostic Significance of FGFR2 in Invasive Breast Carcinoma

SIMPLE SUMMARY: FGFR2-ER-PR crosstalk leads to hormone-independent progression of breast cancer. In vitro, FGFR2 stimulates PR transcriptional activity and mediates resistance to anti-ER therapies. The postulated poor prognostic effect of FGFR2 overexpression has not been confirmed at clinical level...

Descripción completa

Detalles Bibliográficos
Autores principales:	Braun, Marcin, Piasecka, Dominika, Tomasik, Bartlomiej, Mieczkowski, Kamil, Stawiski, Konrad, Zielinska, Aleksandra, Kopczynski, Janusz, Nejc, Dariusz, Kordek, Radzislaw, Sadej, Rafal, Romanska, Hanna M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564845/ https://www.ncbi.nlm.nih.gov/pubmed/32971804 http://dx.doi.org/10.3390/cancers12092713

Ejemplares similares

FGF7/FGFR2–JunB signalling counteracts the effect of progesterone in luminal breast cancer
por: Mieczkowski, Kamil, et al.
Publicado: (2022)

FGFs/FGFRs-dependent signalling in regulation of steroid hormone receptors – implications for therapy of luminal breast cancer
por: Piasecka, Dominika, et al.
Publicado: (2019)

A ‘Real-Life’ Experience on Automated Digital Image Analysis of FGFR2 Immunohistochemistry in Breast Cancer
por: Braun, Marcin, et al.
Publicado: (2020)

MicroRNAs in regulation of triple-negative breast cancer progression
por: Piasecka, Dominika, et al.
Publicado: (2018)

Upregulation of HIF1-α via an NF-κB/COX2 pathway confers proliferative dominance of HER2-negative ductal carcinoma in situ cells in response to inflammatory stimuli
por: Piasecka, Dominika, et al.
Publicado: (2020)

FGFR2-Driven Signaling Counteracts Tamoxifen Effect on ERα-Positive Breast Cancer Cells
por: Turczyk, Lukasz, et al.
Publicado: (2017)

Interactions between FGFR2 and RSK2—implications for breast cancer prognosis
por: Czaplinska, Dominika, et al.
Publicado: (2016)

Profiling of Invasive Breast Carcinoma Circulating Tumour Cells—Are We Ready for the ‘Liquid’ Revolution?
por: Braun, Marcin, et al.
Publicado: (2019)

Fibroblast growth factor signalling induces loss of progesterone receptor in breast cancer cells
por: Piasecka, Dominika, et al.
Publicado: (2016)

Subtype-Specific Tumour Immune Microenvironment in Risk of Recurrence of Ductal Carcinoma In Situ: Prognostic Value of HER2
por: Solek, Julia, et al.
Publicado: (2022)

Ossifying fasciitis at an extraordinary site – a case report and analysis of diagnostic pitfalls
por: Kowalczyk, Łukasz, et al.
Publicado: (2019)

The diagnostic challenge in pulmonary tumour embolism in cancer: a case report and literature review
por: Zielińska, Aleksandra, et al.
Publicado: (2021)

FGFR2 Controls Growth, Adhesion and Migration of Nontumorigenic Human Mammary Epithelial Cells by Regulation of Integrin β1 Degradation
por: Mieczkowski, Kamil, et al.
Publicado: (2023)

Lack of CD151/integrin α3β1 complex is predictive of poor outcome in node-negative lobular breast carcinoma: opposing roles of CD151 in invasive lobular and ductal breast cancers
por: Romanska, Hanna M, et al.
Publicado: (2015)

Intratumor heterogeneity and tissue distribution of KRAS mutation in non-small cell lung cancer: implications for detection of mutated KRAS oncogene in exhaled breath condensate
por: Kordiak, Jacek, et al.
Publicado: (2018)

Extracellular miRNAs as Biomarkers of Head and Neck Cancer Progression and Metastasis
por: Nowicka, Zuzanna, et al.
Publicado: (2019)

MET-Pyk2 Axis Mediates Acquired Resistance to FGFR Inhibition in Cancer Cells
por: Kitowska, Kamila, et al.
Publicado: (2021)

Pure hepatocellular carcinoma originates from an ectopic liver nodule located in the pancreas
por: Braun, Marcin, et al.
Publicado: (2017)

p38 Mediates Resistance to FGFR Inhibition in Non-Small Cell Lung Cancer
por: Zarczynska, Izabela, et al.
Publicado: (2021)

Primary small-cell carcinoma of the palate – the second case report worldwide
por: Kozak-Rusinek, Agnieszka, et al.
Publicado: (2016)

A malignant astrocytoma with uncommon angiocentric features and dot-like EMA expression
por: Kuncman, Wojciech, et al.
Publicado: (2018)

Melatonin, but not melatonin receptor agonists Neu-P11 and Neu-P67, attenuates TNBS-induced colitis in mice
por: Zielińska, Marta, et al.
Publicado: (2016)

Experimental colitis in mice is attenuated by topical administration of chlorogenic acid
por: Zatorski, Hubert, et al.
Publicado: (2015)

MiR-21, miR-34a, miR-125b, miR-181d and miR-648 levels inversely correlate with MGMT and TP53 expression in primary glioblastoma patients
por: Jesionek-Kupnicka, Dorota, et al.
Publicado: (2017)

Assessment of the TGFB1 gene expression and methylation status of the promoter region in patients with colorectal cancer
por: Wodziński, Damian, et al.
Publicado: (2022)

Antinociceptive potency of a fluorinated cyclopeptide Dmt-c[D-Lys-Phe-p-CF(3)-Phe-Asp]NH(2)
por: Piekielna-Ciesielska, Justyna, et al.
Publicado: (2018)

AdipoRon, an Orally Active, Synthetic Agonist of AdipoR1 and AdipoR2 Receptors Has Gastroprotective Effect in Experimentally Induced Gastric Ulcers in Mice
por: Zatorski, Hubert, et al.
Publicado: (2021)

ABCG2 Gene and ABCG2 Protein Expression in Colorectal Cancer—In Silico and Wet Analysis
por: Sałagacka-Kubiak, Aleksandra, et al.
Publicado: (2023)

G protein-coupled estrogen receptor mediates anti-inflammatory action in Crohn’s disease
por: Jacenik, Damian, et al.
Publicado: (2019)

Raman imaging at biological interfaces: applications in breast cancer diagnosis
por: Surmacki, Jakub, et al.
Publicado: (2013)

Does vimentin help to delineate the so-called 'basal type breast cancer'?
por: Kusinska, Renata U, et al.
Publicado: (2009)

MicroRNA profile and iron-related gene expression in hepatitis C-related hepatocellular carcinoma: a preliminary study
por: Krupa, Renata, et al.
Publicado: (2019)

Analysis of Human Colon by Raman Spectroscopy and Imaging-Elucidation of Biochemical Changes in Carcinogenesis
por: Brozek-Pluska, Beata, et al.
Publicado: (2019)

Label-free diagnostics and cancer surgery Raman spectra guidance for the human colon at different excitation wavelengths
por: Brozek-Pluska, Beata, et al.
Publicado: (2019)

The prognostic value of red cell distribution width (RDW), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) in radiotherapy for oropharyngeal cancer
por: Staniewska, Emilia, et al.
Publicado: (2021)

Current and future applications of liquid biopsy in non-small-cell lung cancer—a narrative review
por: Tomasik, Bartłomiej, et al.
Publicado: (2023)

The Anti-Inflammatory Effect of Acidic Mammalian Chitinase Inhibitor OAT-177 in DSS-Induced Mouse Model of Colitis
por: Mazur, Marzena, et al.
Publicado: (2022)

Basal keratin expression in breast cancer by quantification of mRNA and by immunohistochemistry
por: Kordek, Radzislaw, et al.
Publicado: (2010)

Intertumoral Heterogeneity of Primary Breast Tumors and Synchronous Axillary Lymph Node Metastases Reflected in IHC-Assessed Expression of Routine and Nonstandard Biomarkers
por: Kuncman, Wojciech, et al.
Publicado: (2021)

Age-related changes in human sperm DNA integrity
por: Rosiak-Gill, Aleksandra, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_p2at715jsv1b7furccgaoggv50