Detection of Germline Mutations in a Cohort of 139 Patients with Bilateral Breast Cancer by Multi-Gene Panel Testing: Impact of Pathogenic Variants in Other Genes beyond BRCA1/2

SIMPLE SUMMARY: Many bilateral breast cancer patients with increased hereditary susceptibility to breast cancer result negative for BRCA1 or BRCA2 pathogenic variants and, thus, need a further genetic testing through a broader gene panel. Some patients with negative test result for BRCA1/2 pathogeni...

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Detalles Bibliográficos
Autores principales: Fanale, Daniele, Incorvaia, Lorena, Filorizzo, Clarissa, Bono, Marco, Fiorino, Alessia, Calò, Valentina, Brando, Chiara, Corsini, Lidia Rita, Barraco, Nadia, Badalamenti, Giuseppe, Russo, Antonio, Bazan, Viviana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564956/
https://www.ncbi.nlm.nih.gov/pubmed/32854451
http://dx.doi.org/10.3390/cancers12092415

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