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Near-Infrared Photoimmunotherapy Combined with CTLA4 Checkpoint Blockade in Syngeneic Mouse Cancer Models

Near infrared photoimmunotherapy (NIR-PIT) is a newly developed and highly selective cancer treatment that induces necrotic/immunogenic cell death. It employs a monoclonal antibody (mAb) conjugated to a photo-absorber dye, IRDye700DX, which is activated by NIR light. Tumor-targeting NIR-PIT is also...

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Detalles Bibliográficos
Autores principales: Maruoka, Yasuhiro, Furusawa, Aki, Okada, Ryuhei, Inagaki, Fuyuki, Fujimura, Daiki, Wakiyama, Hiroaki, Kato, Takuya, Nagaya, Tadanobu, Choyke, Peter L., Kobayashi, Hisataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564971/
https://www.ncbi.nlm.nih.gov/pubmed/32937841
http://dx.doi.org/10.3390/vaccines8030528

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