Explorative Combined Lipid and Transcriptomic Profiling of Substantia Nigra and Putamen in Parkinson’s Disease

Parkinson’s disease (PD) is characterized by the loss of dopaminergic neurons from the substantia nigra (SN) that project to the dorsal striatum (caudate-putamen). To better understand the molecular mechanisms underlying PD, we performed combined lipid profiling and RNA sequencing of SN and putamen...

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Detalles Bibliográficos
Autores principales: Xicoy, Helena, Brouwers, Jos F., Wieringa, Bé, Martens, Gerard J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7564986/
https://www.ncbi.nlm.nih.gov/pubmed/32858884
http://dx.doi.org/10.3390/cells9091966

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