Matrix Metalloproteinase-11 Promotes Early Mouse Mammary Gland Tumor Growth through Metabolic Reprogramming and Increased IGF1/AKT/FoxO1 Signaling Pathway, Enhanced ER Stress and Alteration in Mitochondrial UPR

Matrix metalloproteinase 11 (MMP11) is an extracellular proteolytic enzyme belonging to the matrix metalloproteinase (MMP11) family. These proteases are involved in extracellular matrix (ECM) remodeling and activation of latent factors. MMP11 is a negative regulator of adipose tissue development and...

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Detalles Bibliográficos
Autores principales: Tan, Bing, Jaulin, Amélie, Bund, Caroline, Outilaft, Hassiba, Wendling, Corinne, Chenard, Marie-Pierrette, Alpy, Fabien, Cicek, A. Ercüment, Namer, Izzie J., Tomasetto, Catherine, Dali-Youcef, Nassim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565046/
https://www.ncbi.nlm.nih.gov/pubmed/32825455
http://dx.doi.org/10.3390/cancers12092357

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