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CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification
Sarcoidosis is a granulomatous disorder of unknown etiology characterized by noncaseating granulomas virtually in every organ and tissue. This finding represents the most important diagnostic clue to reach a correct definition of sarcoidosis, although the biopsy is invasive and has several risk proc...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565100/ https://www.ncbi.nlm.nih.gov/pubmed/32962242 http://dx.doi.org/10.3390/jcm9093028 |
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author | Tana, Claudio Donatiello, Iginio Coppola, Maria Gabriella Ricci, Fabrizio Maccarone, Marica Tina Ciarambino, Tiziana Cipollone, Francesco Giamberardino, Maria Adele |
author_facet | Tana, Claudio Donatiello, Iginio Coppola, Maria Gabriella Ricci, Fabrizio Maccarone, Marica Tina Ciarambino, Tiziana Cipollone, Francesco Giamberardino, Maria Adele |
author_sort | Tana, Claudio |
collection | PubMed |
description | Sarcoidosis is a granulomatous disorder of unknown etiology characterized by noncaseating granulomas virtually in every organ and tissue. This finding represents the most important diagnostic clue to reach a correct definition of sarcoidosis, although the biopsy is invasive and has several risk procedures. Several efforts are made to suspect the diagnosis of sarcoidosis by combining noninvasive elements, in particular from imaging, though these findings are often nonspecific and reflect the wide multifactorial pathogenesis. Every effort should be made to obtain a detailed radiological picture that, if associated with a suggestive clinical picture, could avoid the need of biopsy in some specific cases. In this narrative review, we aim to describe main computed tomography (CT) features of pulmonary and abdominal sarcoidosis, by reporting strengths and limits of this technique, in particular for the identification of extrapulmonary, isolated disease. |
format | Online Article Text |
id | pubmed-7565100 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75651002020-10-26 CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification Tana, Claudio Donatiello, Iginio Coppola, Maria Gabriella Ricci, Fabrizio Maccarone, Marica Tina Ciarambino, Tiziana Cipollone, Francesco Giamberardino, Maria Adele J Clin Med Review Sarcoidosis is a granulomatous disorder of unknown etiology characterized by noncaseating granulomas virtually in every organ and tissue. This finding represents the most important diagnostic clue to reach a correct definition of sarcoidosis, although the biopsy is invasive and has several risk procedures. Several efforts are made to suspect the diagnosis of sarcoidosis by combining noninvasive elements, in particular from imaging, though these findings are often nonspecific and reflect the wide multifactorial pathogenesis. Every effort should be made to obtain a detailed radiological picture that, if associated with a suggestive clinical picture, could avoid the need of biopsy in some specific cases. In this narrative review, we aim to describe main computed tomography (CT) features of pulmonary and abdominal sarcoidosis, by reporting strengths and limits of this technique, in particular for the identification of extrapulmonary, isolated disease. MDPI 2020-09-20 /pmc/articles/PMC7565100/ /pubmed/32962242 http://dx.doi.org/10.3390/jcm9093028 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Tana, Claudio Donatiello, Iginio Coppola, Maria Gabriella Ricci, Fabrizio Maccarone, Marica Tina Ciarambino, Tiziana Cipollone, Francesco Giamberardino, Maria Adele CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification |
title | CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification |
title_full | CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification |
title_fullStr | CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification |
title_full_unstemmed | CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification |
title_short | CT Findings in Pulmonary and Abdominal Sarcoidosis. Implications for Diagnosis and Classification |
title_sort | ct findings in pulmonary and abdominal sarcoidosis. implications for diagnosis and classification |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565100/ https://www.ncbi.nlm.nih.gov/pubmed/32962242 http://dx.doi.org/10.3390/jcm9093028 |
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