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Tryptophanyl-tRNA Synthetase 1 Signals Activate TREM-1 via TLR2 and TLR4

Tryptophanyl-tRNA synthetase 1 (WARS1) is an endogenous ligand of mammalian Toll-like receptors (TLR) 2 and TLR4. Microarray data, using mRNA from WARS1-treated human peripheral blood mononuclear cells (PBMCs), had indicated WARS1 to mainly activate innate inflammatory responses. However, exact mole...

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Detalles Bibliográficos
Autores principales:	Nguyen, Tram T. T., Yoon, Hee Kyeong, Kim, Yoon Tae, Choi, Yun Hui, Lee, Won-Kyu, Jin, Mirim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565148/ https://www.ncbi.nlm.nih.gov/pubmed/32899943 http://dx.doi.org/10.3390/biom10091283

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