Cargando…

Tissue Immune Profile: A Tool to Predict Response to Neoadjuvant Therapy in Triple Negative Breast Cancer

SIMPLE SUMMARY: Pathological complete response (pCR) after neoadjuvant chemotherapy can predict survival outcomes in patients with early triple negative breast cancer (TNBC). The immune microenvironment can affect response to chemotherapy. We combined several immune-related biomarkers (TILs, PD-L1 a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cerbelli, Bruna, Scagnoli, Simone, Mezi, Silvia, De Luca, Alessandro, Pisegna, Simona, Amabile, Maria Ida, Roberto, Michela, Fortunato, Lucio, Costarelli, Leopoldo, Pernazza, Angelina, Strigari, Lidia, Della Rocca, Carlo, Marchetti, Paolo, d’Amati, Giulia, Botticelli, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565153/ https://www.ncbi.nlm.nih.gov/pubmed/32947953 http://dx.doi.org/10.3390/cancers12092648

Ejemplares similares

PD-L1 Expression in TNBC: A Predictive Biomarker of Response to Neoadjuvant Chemotherapy?
por: Cerbelli, Bruna, et al.
Publicado: (2017)

Standard of Care and Promising New Agents for the Treatment of Mesenchymal Triple-Negative Breast Cancer
por: Mezi, Silvia, et al.
Publicado: (2021)

Anti–PD-1 and Anti–PD-L1 in Head and Neck Cancer: A Network Meta-Analysis
por: Botticelli, Andrea, et al.
Publicado: (2021)

Overexpression in metastatic breast cancer supports Syndecan-1 as a marker of invasiveness and poor prognosis
por: Cerbelli, Bruna, et al.
Publicado: (2022)

Circulating CD137(+) T Cell Levels Are Correlated with Response to Pembrolizumab Treatment in Advanced Head and Neck Cancer Patients
por: Cirillo, Alessio, et al.
Publicado: (2023)

The Agnostic Role of Site of Metastasis in Predicting Outcomes in Cancer Patients Treated with Immunotherapy
por: Botticelli, Andrea, et al.
Publicado: (2020)

Atypical cellular neurothekeoma (ACN) of the elderly: case report and brief review of the literature
por: D’Alessandris, Nicoletta, et al.
Publicado: (2020)

The Role of Soluble LAG3 and Soluble Immune Checkpoints Profile in Advanced Head and Neck Cancer: A Pilot Study
por: Botticelli, Andrea, et al.
Publicado: (2021)

Pathological examination of breast cancer samples before and after neoadjuvant therapy: recommendations from the Italian Group for the Study of Breast Pathology - Italian Society of Pathology (GIPaM-SIAPeC)
por: Fusco, Nicola, et al.
Publicado: (2022)

Tryptophan Catabolism as Immune Mechanism of Primary Resistance to Anti-PD-1
por: Botticelli, Andrea, et al.
Publicado: (2020)

Extremely late-onset pulmonary metastasis from uterine PEComa
por: Ascione, Andrea, et al.
Publicado: (2022)

Early histologic findings of pulmonary SARS-CoV-2 infection detected in a surgical specimen
por: Pernazza, Angelina, et al.
Publicado: (2020)

The role of opioids in cancer response to immunotherapy
por: Botticelli, Andrea, et al.
Publicado: (2021)

The sexist behaviour of immune checkpoint inhibitors in cancer therapy?
por: Botticelli, Andrea, et al.
Publicado: (2017)

Xanthoma of rib: a case report and review of the literature
por: Mottola, Emilia, et al.
Publicado: (2023)

Circulating CD137(+) T Cells Correlate with Improved Response to Anti-PD1 Immunotherapy in Patients with Cancer
por: Zizzari, Ilaria Grazia, et al.
Publicado: (2022)

The role of immune profile in predicting outcomes in cancer patients treated with immunotherapy
por: Botticelli, Andrea, et al.
Publicado: (2022)

Weekly chemotherapy as first line treatment in frail head and neck cancer patients in the immunotherapy era
por: Botticelli, Andrea, et al.
Publicado: (2021)

RNA‐seq profiling reveals different pathways between remodeled vessels and myocardium in hypertrophic cardiomyopathy
por: Pisano, Annalinda, et al.
Publicado: (2022)

Primary squamous cell carcinoma of major salivary gland: “Sapienza Head and Neck Unit” clinical recommendations
por: Mezi, Silvia, et al.
Publicado: (2020)

Evaluating programmed death‐ligand 1 (PD‐L1) in head and neck squamous cell carcinoma: concordance between the 22C3 PharmDx assay and the SP263 assay on whole sections from a multicentre study
por: Cerbelli, Bruna, et al.
Publicado: (2021)

Degradation Rate of 5-Fluorouracil in Metastatic Colorectal Cancer: A New Predictive Outcome Biomarker?
por: Botticelli, Andrea, et al.
Publicado: (2016)

The Impact of Drug–Drug Interactions on the Toxicity Profile of Combined Treatment with BRAF and MEK Inhibitors in Patients with BRAF-Mutated Metastatic Melanoma
por: Mezi, Silvia, et al.
Publicado: (2023)

A nomogram to predict survival in non-small cell lung cancer patients treated with nivolumab
por: Botticelli, Andrea, et al.
Publicado: (2019)

Quantitative CT texture analysis in predicting PD-L1 expression in locally advanced or metastatic NSCLC patients
por: Bracci, Stefano, et al.
Publicado: (2021)

Intraductal Proliferative Lesions of the Breast—Terminology and Biology Matter: Premalignant Lesions or Preinvasive Cancer?
por: Costarelli, Leopoldo, et al.
Publicado: (2012)

Genomic and Immune Approach in Platinum Refractory HPV-Negative Head and Neck Squamous Cell Carcinoma Patients Treated with Immunotherapy: A Novel Combined Profile
por: Mezi, Silvia, et al.
Publicado: (2022)

Radiologic-pathologic correlation in breast cancer: do MRI biomarkers correlate with pathologic features and molecular subtypes?
por: Galati, Francesca, et al.
Publicado: (2022)

Molecular profiling of male breast cancer by multigene panel testing: Implications for precision oncology
por: Valentini, Virginia, et al.
Publicado: (2023)

Immune effects of CDK4/6 inhibitors in patients with HR(+)/HER2(−) metastatic breast cancer: Relief from immunosuppression is associated with clinical response
por: Scirocchi, Fabio, et al.
Publicado: (2022)

Results of Adrenalectomy for Isolated, Metachronous Metastasis of Breast Cancer: A Retrospective Cohort Study
por: Illuminati, Giulio, et al.
Publicado: (2021)

Retrospective Evaluation of the Effectiveness of a Synthetic Glue and a Fibrin-Based Sealant for the Prevention of Seroma Following Axillary Dissection in Breast Cancer Patients
por: De Luca, Alessandro, et al.
Publicado: (2020)

Small hepatic veins Budd-Chiari syndrome and paroxysmal nocturnal hemoglobinuria - The association of two rare entities: a case report
por: Gioia, Stefania, et al.
Publicado: (2020)

Severe Impact of Covid-19 Pandemic on Breast Cancer Care in Italy: A Senonetwork National Survey
por: Fortunato, Lucio, et al.
Publicado: (2021)

Dirofilaria repens Infection Mimicking Lung Melanoma Metastasis
por: Oliva, A, et al.
Publicado: (2019)

The Impact of Locoregional Treatment on Response to Nivolumab in Advanced Platinum Refractory Head and Neck Cancer: The Need Trial
por: Botticelli, Andrea, et al.
Publicado: (2020)

Lean body mass wasting and toxicity in early breast cancer patients receiving anthracyclines
por: Mazzuca, Federica, et al.
Publicado: (2018)

A network approach to define the predictive role of immune profile on tumor response and toxicity of anti PD-1 single agent immunotherapy in patients with solid tumors
por: Mezi, Silvia, et al.
Publicado: (2023)

Intravoxel Incoherent Motion (IVIM) MR Quantification in Locally Advanced Cervical Cancer (LACC): Preliminary Study on Assessment of Tumor Aggressiveness and Response to Neoadjuvant Chemotherapy
por: Dolciami, Miriam, et al.
Publicado: (2022)

Can IDO activity predict primary resistance to anti-PD-1 treatment in NSCLC?
por: Botticelli, Andrea, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_te6nhua5eoega13eefggk36b5i