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The FMS like Tyrosine Kinase 3 (FLT3) Is Overexpressed in a Subgroup of Multiple Myeloma Patients with Inferior Prognosis

Therapy resistance remains a major challenge in the management of multiple myeloma (MM). We evaluated the expression of FLT3 tyrosine kinase receptor (FLT3, CD135) in myeloma cells as a possible clonal driver. FLT3 expression was analyzed in bone marrow biopsies of patients with monoclonal gammopath...

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Detalles Bibliográficos
Autores principales: Steiner, Normann, Jöhrer, Karin, Plewan, Selina, Brunner-Véber, Andrea, Göbel, Georg, Nachbaur, David, Wolf, Dominik, Gunsilius, Eberhard, Untergasser, Gerold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565188/
https://www.ncbi.nlm.nih.gov/pubmed/32825035
http://dx.doi.org/10.3390/cancers12092341