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RAS Subcellular Localization Inversely Regulates Thyroid Tumor Growth and Dissemination

SIMPLE SUMMARY: RAS mutations occur frequently in thyroid tumors, but the extent to which they are associated to tumor aggressiveness is still uncertain. HRAS proteins occupy different subcellular localizations, from which they regulate distinct biochemical processes. Herein, we demonstrate that the...

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Detalles Bibliográficos
Autores principales: García-Ibáñez, Yaiza, Riesco-Eizaguirre, Garcilaso, Santisteban, Pilar, Casar, Berta, Crespo, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565207/
https://www.ncbi.nlm.nih.gov/pubmed/32927904
http://dx.doi.org/10.3390/cancers12092588