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Assessment of SARS-CoV-2 in the Cerumen of COVID-19-Positive Patients

OBJECTIVE: To evaluate the presence of SARS-CoV-2 virus in the cerumen of patients with COVID-19. METHODS: A prospective study was conducted in a tertiary care pandemic hospital. Sixty COVID-19 patients with cerumen in their external auditory canals were included in the study. Swabs were taken from...

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Autores principales: Islamoglu, Yuce, Bercin, Sami, Aydogan, Sibel, Sener, Alp, Tanriverdi, Fatih, Gunaydin, Gul Pamukcu, Dinc, Bedia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565248/
https://www.ncbi.nlm.nih.gov/pubmed/33054373
http://dx.doi.org/10.1177/0145561320966067
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author Islamoglu, Yuce
Bercin, Sami
Aydogan, Sibel
Sener, Alp
Tanriverdi, Fatih
Gunaydin, Gul Pamukcu
Dinc, Bedia
author_facet Islamoglu, Yuce
Bercin, Sami
Aydogan, Sibel
Sener, Alp
Tanriverdi, Fatih
Gunaydin, Gul Pamukcu
Dinc, Bedia
author_sort Islamoglu, Yuce
collection PubMed
description OBJECTIVE: To evaluate the presence of SARS-CoV-2 virus in the cerumen of patients with COVID-19. METHODS: A prospective study was conducted in a tertiary care pandemic hospital. Sixty COVID-19 patients with cerumen in their external auditory canals were included in the study. Swabs were taken from the external auditory canal of the patients by an experienced otolaryngologist with the test swab. Sampling was done by rotating the sample swab 360° 10 times in each external auditory canal for a total of 20 times. After collection, swabs were placed into 2 mL of the sterile viral transport medium (various manufacturers), then transported and tested as soon as possible after collection. RESULTS: SARS-CoV-2 was not detected in the cerumen polymerase chain reaction (PCR) samples of any of the 60 patients with positive nasopharyngeal/oropharyngeal swabs. CONCLUSION: Cerumen cleaning is one of the most common procedures performed by otolaryngologists, and care should be taken during the procedure or due to the possibility of infection from the resulting contaminants. The cerumen contains the secretions of the glands in the external auditory canal and may contain certain pathogens that are actively found in the body. The presence of hepatitis B virus in the cerumen was examined and isolated in the cerumen. In our study, the presence of SARS-CoV-2 virus in the cerumen was evaluated in SARS-CoV-2 PCR-positive patients. SARS-CoV-2 virus was not detected in the cerumen samples of any of the patients.
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spelling pubmed-75652482020-10-16 Assessment of SARS-CoV-2 in the Cerumen of COVID-19-Positive Patients Islamoglu, Yuce Bercin, Sami Aydogan, Sibel Sener, Alp Tanriverdi, Fatih Gunaydin, Gul Pamukcu Dinc, Bedia Ear Nose Throat J Clinical Study OBJECTIVE: To evaluate the presence of SARS-CoV-2 virus in the cerumen of patients with COVID-19. METHODS: A prospective study was conducted in a tertiary care pandemic hospital. Sixty COVID-19 patients with cerumen in their external auditory canals were included in the study. Swabs were taken from the external auditory canal of the patients by an experienced otolaryngologist with the test swab. Sampling was done by rotating the sample swab 360° 10 times in each external auditory canal for a total of 20 times. After collection, swabs were placed into 2 mL of the sterile viral transport medium (various manufacturers), then transported and tested as soon as possible after collection. RESULTS: SARS-CoV-2 was not detected in the cerumen polymerase chain reaction (PCR) samples of any of the 60 patients with positive nasopharyngeal/oropharyngeal swabs. CONCLUSION: Cerumen cleaning is one of the most common procedures performed by otolaryngologists, and care should be taken during the procedure or due to the possibility of infection from the resulting contaminants. The cerumen contains the secretions of the glands in the external auditory canal and may contain certain pathogens that are actively found in the body. The presence of hepatitis B virus in the cerumen was examined and isolated in the cerumen. In our study, the presence of SARS-CoV-2 virus in the cerumen was evaluated in SARS-CoV-2 PCR-positive patients. SARS-CoV-2 virus was not detected in the cerumen samples of any of the patients. SAGE Publications 2021-04 /pmc/articles/PMC7565248/ /pubmed/33054373 http://dx.doi.org/10.1177/0145561320966067 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Clinical Study
Islamoglu, Yuce
Bercin, Sami
Aydogan, Sibel
Sener, Alp
Tanriverdi, Fatih
Gunaydin, Gul Pamukcu
Dinc, Bedia
Assessment of SARS-CoV-2 in the Cerumen of COVID-19-Positive Patients
title Assessment of SARS-CoV-2 in the Cerumen of COVID-19-Positive Patients
title_full Assessment of SARS-CoV-2 in the Cerumen of COVID-19-Positive Patients
title_fullStr Assessment of SARS-CoV-2 in the Cerumen of COVID-19-Positive Patients
title_full_unstemmed Assessment of SARS-CoV-2 in the Cerumen of COVID-19-Positive Patients
title_short Assessment of SARS-CoV-2 in the Cerumen of COVID-19-Positive Patients
title_sort assessment of sars-cov-2 in the cerumen of covid-19-positive patients
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565248/
https://www.ncbi.nlm.nih.gov/pubmed/33054373
http://dx.doi.org/10.1177/0145561320966067
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