An Evolutionary Cancer Epigenetic Approach Revealed DNA Hypermethylation of Ultra-Conserved Non-Coding Elements in Squamous Cell Carcinoma of Different Mammalian Species

Background: Ultra-conserved non-coding elements (UCNEs) are genomic sequences that exhibit > 95% sequence identity between humans, mammals, birds, reptiles, and fish. Recent findings reported their functional role in cancer. The aim of this study was to evaluate the DNA methylation modifications...

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Detalles Bibliográficos
Autores principales: Morandi, Luca, Sabattini, Silvia, Renzi, Andrea, Rigillo, Antonella, Bettini, Giuliano, Dervas, Eva, Schauer, Alexandria, Morandi, Marco, Gissi, Davide B., Tarsitano, Achille, Evangelisti, Stefania, Tonon, Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565279/
https://www.ncbi.nlm.nih.gov/pubmed/32933205
http://dx.doi.org/10.3390/cells9092092

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