Neoplastic Cells are the Major Source of MT-MMPs in IDH1-Mutant Glioma, Thus Enhancing Tumor-Cell Intrinsic Brain Infiltration

SIMPLE SUMMARY: Most primary brain tumors infiltrate the surrounding brain even before the time of diagnosis and therefore cannot be removed completely. Matrix metalloproteases can degrade the extracellular proteins of the brain and thereby allow for the brain infiltration of glioma cells. Here, we...

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Detalles Bibliográficos
Autores principales: Thome, Ina, Lacle, Raphael, Voß, Andreas, Bortolussi, Ginette, Pantazis, Georgios, Schmidt, Ansgar, Conrad, Catharina, Jacob, Ralf, Timmesfeld, Nina, Bartsch, Jörg W., Pagenstecher, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565296/
https://www.ncbi.nlm.nih.gov/pubmed/32872536
http://dx.doi.org/10.3390/cancers12092456

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