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Tsc1 Regulates the Proliferation Capacity of Bone-Marrow Derived Mesenchymal Stem Cells

TSC1 is a tumor suppressor that inhibits cell growth via negative regulation of the mammalian target of rapamycin complex (mTORC1). TSC1 mutations are associated with Tuberous Sclerosis Complex (TSC), characterized by multiple benign tumors of mesenchymal and epithelial origin. TSC1 modulates self-r...

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Detalles Bibliográficos
Autores principales:	Guijarro, Maria V., Danielson, Laura S., Cañamero, Marta, Nawab, Akbar, Abrahan, Carolina, Hernando, Eva, Palmer, Glyn D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565438/ https://www.ncbi.nlm.nih.gov/pubmed/32927859 http://dx.doi.org/10.3390/cells9092072

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