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An Exploratory Association Analysis of ABCB(1) rs1045642 and ABCB(1) rs4148738 with Non-Major Bleeding Risk in Atrial Fibrillation Patients Treated with Dabigatran or Apixaban

(1) Background: The approach of bleeding complications in patients treated with non-vitamin K oral anticoagulants (NOACs) represents an important issue in clinical practice. Both dabigatran and apixaban are substrates for P-glycoprotein and, therefore, ABCB(1) gene variations may be useful in indivi...

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Detalles Bibliográficos
Autores principales: Roşian, Adela-Nicoleta, Iancu, Mihaela, Trifa, Adrian Pavel, Roşian, Ştefan Horia, Mada, Cristina, Gocan, Cornelia Paula, Niţă, Teodora, Istratoaie, Sabina, Boarescu, Paul-Mihai, Buzoianu, Anca Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565454/
https://www.ncbi.nlm.nih.gov/pubmed/32961964
http://dx.doi.org/10.3390/jpm10030133