Cancer Acidity and Hypertonicity Contribute to Dysfunction of Tumor-Associated Dendritic Cells: Potential Impact on Antigen Cross-Presentation Machinery

Macrophages (MΦ) and dendritic cells (DC), major players of the mononuclear phagocyte system (MoPh), are potent antigen presenting cells that steadily sense and respond to signals from the surrounding microenvironment, leading to either immunogenic or tolerogenic outcomes. Next to classical MHC-I/MH...

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Detalles Bibliográficos
Autores principales: Burgdorf, Sven, Porubsky, Stefan, Marx, Alexander, Popovic, Zoran V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565485/
https://www.ncbi.nlm.nih.gov/pubmed/32847079
http://dx.doi.org/10.3390/cancers12092403

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