Oligonucleotides and microRNAs Targeting Telomerase Subunits in Cancer Therapy

Telomerase provides cancer cells with replicative immortality, and its overexpression serves as a near-universal marker of cancer. Anti-cancer therapeutics targeting telomerase have garnered interest as possible alternatives to chemotherapy and radiotherapy. Oligonucleotide-based therapies that inhi...

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Detalles Bibliográficos
Autores principales: Eckburg, Adam, Dein, Joshua, Berei, Joseph, Schrank, Zachary, Puri, Neelu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565511/
https://www.ncbi.nlm.nih.gov/pubmed/32825005
http://dx.doi.org/10.3390/cancers12092337

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