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Inhibition of Caspases Improves Non-Viral T Cell Receptor Editing

SIMPLE SUMMARY: Chimeric antigen receptor (CAR) T cells have shown promising results in cancer treatment. They can be generated with T cells from patients for personalized therapy or donors for off-the-shelf products. A critical step in producing the allogeneic CAR T cells is to knock out the endoge...

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Detalles Bibliográficos
Autores principales:	Wang, Chunxi, Chang, Chun-Chi, Wang, Liangli, Yuan, Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565551/ https://www.ncbi.nlm.nih.gov/pubmed/32933048 http://dx.doi.org/10.3390/cancers12092603

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