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FGF2 Inhibits Early Pancreatic Lineage Specification during Differentiation of Human Embryonic Stem Cells

Growth factors are important regulators during organ development. For many vertebrates (but not humans) it is known how they contribute to the formation and expansion of PDX1-positive cells during pancreas organogenesis. Here, the effects of the fibroblast growth factors FGF2, FGF7, FGF10, and epide...

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Detalles Bibliográficos
Autores principales: Dettmer, Rabea, Cirksena, Karsten, Münchhoff, Julia, Kresse, Jasmin, Diekmann, Ulf, Niwolik, Isabell, Buettner, Falk F. R., Naujok, Ortwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565644/
https://www.ncbi.nlm.nih.gov/pubmed/32825270
http://dx.doi.org/10.3390/cells9091927

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