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Targeted Activation of T Cells with IL-2-Coupled Nanoparticles

Interleukin-2 (IL-2) is a T cell growth factor particularly required in regulatory T cell maintenance and memory T cell responses. High-dose IL-2 treatment was the first FDA-approved immunotherapy for cancer, while low-dose IL-2 administration has shown promise in allograft rejection and autoimmune...

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Detalles Bibliográficos
Autores principales: Raker, Verena K., Becker, Christian, Landfester, Katharina, Steinbrink, Kerstin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565705/
https://www.ncbi.nlm.nih.gov/pubmed/32917054
http://dx.doi.org/10.3390/cells9092063