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Pneumocystis jirevocii and SARS-CoV-2 Co-Infection: A Common Feature in Transplant Recipients?
COVID-19 might potentially give rise to a more severe infection in solid organ transplant recipients due to their chronic immunosuppression. These patients are at a higher risk of developing concurrent or secondary bacterial and fungal infections. Co-infections can increase systemic inflammation inf...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565862/ https://www.ncbi.nlm.nih.gov/pubmed/32962148 http://dx.doi.org/10.3390/vaccines8030544 |
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author | De Francesco, Maria A. Alberici, Federico Bossini, Nicola Scolari, Francesco Pascucci, Federico Tomasoni, Gabriele Caruso, Arnaldo |
author_facet | De Francesco, Maria A. Alberici, Federico Bossini, Nicola Scolari, Francesco Pascucci, Federico Tomasoni, Gabriele Caruso, Arnaldo |
author_sort | De Francesco, Maria A. |
collection | PubMed |
description | COVID-19 might potentially give rise to a more severe infection in solid organ transplant recipients due to their chronic immunosuppression. These patients are at a higher risk of developing concurrent or secondary bacterial and fungal infections. Co-infections can increase systemic inflammation influencing the prognosis and the severity of the disease, and can in turn lead to an increased need of mechanical ventilation, antibiotic therapy and to a higher mortality. Here we describe, for the first time in Europe, a fatal case of co-infection between SARS-CoV-2 and Pneumocystis jirevocii in a kidney transplant recipient. |
format | Online Article Text |
id | pubmed-7565862 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-75658622020-10-26 Pneumocystis jirevocii and SARS-CoV-2 Co-Infection: A Common Feature in Transplant Recipients? De Francesco, Maria A. Alberici, Federico Bossini, Nicola Scolari, Francesco Pascucci, Federico Tomasoni, Gabriele Caruso, Arnaldo Vaccines (Basel) Case Report COVID-19 might potentially give rise to a more severe infection in solid organ transplant recipients due to their chronic immunosuppression. These patients are at a higher risk of developing concurrent or secondary bacterial and fungal infections. Co-infections can increase systemic inflammation influencing the prognosis and the severity of the disease, and can in turn lead to an increased need of mechanical ventilation, antibiotic therapy and to a higher mortality. Here we describe, for the first time in Europe, a fatal case of co-infection between SARS-CoV-2 and Pneumocystis jirevocii in a kidney transplant recipient. MDPI 2020-09-18 /pmc/articles/PMC7565862/ /pubmed/32962148 http://dx.doi.org/10.3390/vaccines8030544 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report De Francesco, Maria A. Alberici, Federico Bossini, Nicola Scolari, Francesco Pascucci, Federico Tomasoni, Gabriele Caruso, Arnaldo Pneumocystis jirevocii and SARS-CoV-2 Co-Infection: A Common Feature in Transplant Recipients? |
title | Pneumocystis jirevocii and SARS-CoV-2 Co-Infection: A Common Feature in Transplant Recipients? |
title_full | Pneumocystis jirevocii and SARS-CoV-2 Co-Infection: A Common Feature in Transplant Recipients? |
title_fullStr | Pneumocystis jirevocii and SARS-CoV-2 Co-Infection: A Common Feature in Transplant Recipients? |
title_full_unstemmed | Pneumocystis jirevocii and SARS-CoV-2 Co-Infection: A Common Feature in Transplant Recipients? |
title_short | Pneumocystis jirevocii and SARS-CoV-2 Co-Infection: A Common Feature in Transplant Recipients? |
title_sort | pneumocystis jirevocii and sars-cov-2 co-infection: a common feature in transplant recipients? |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565862/ https://www.ncbi.nlm.nih.gov/pubmed/32962148 http://dx.doi.org/10.3390/vaccines8030544 |
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