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Implications of CLSPN Variants in Cellular Function and Susceptibility to Cancer
Claspin is a multifunctional protein that participates in physiological processes essential for cell homeostasis that are often defective in cancer, namely due to genetic changes. It is conceivable that Claspin gene (CLSPN) alterations may contribute to cancer development. Therefore, CLSPN germline...
Autores principales: | Azenha, Diana, Hernandez-Perez, Santiago, Martin, Yuse, Viegas, Marta S., Martins, Alexandra, Lopes, Maria C., Lam, Eric W. -F., Freire, Raimundo, Martins, Teresa C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565888/ https://www.ncbi.nlm.nih.gov/pubmed/32847043 http://dx.doi.org/10.3390/cancers12092396 |
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