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The Anti-Pseudomonal Peptide D-BMAP18 Is Active in Cystic Fibrosis Sputum and Displays Anti-Inflammatory In Vitro Activity

Most Cystic Fibrosis (CF) patients succumb to airway inflammation and pulmonary infections due to Pseudomonas aeruginosa. D-BMAP18, a membrane-permeabilizing antimicrobial peptide composed of D-amino acids, was evaluated as a possible antibacterial aimed to address this issue. The antipseudomonal ac...

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Detalles Bibliográficos
Autores principales: Degasperi, Margherita, Agostinis, Chiara, Mardirossian, Mario, Maschio, Massimo, Taddio, Andrea, Bulla, Roberta, Scocchi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565916/
https://www.ncbi.nlm.nih.gov/pubmed/32932703
http://dx.doi.org/10.3390/microorganisms8091407

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