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Levetiracetam Reduced the Basal Excitability of the Dentate Gyrus without Restoring Impaired Synaptic Plasticity in Rats with Temporal Lobe Epilepsy

Temporal lobe epilepsy (TLE), the most common type of focal epilepsy, affects learning and memory; these effects are thought to emerge from changes in synaptic plasticity. Levetiracetam (LEV) is a widely used antiepileptic drug that is also associated with the reversal of cognitive dysfunction. The...

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Detalles Bibliográficos
Autores principales: González-H, Guillermo, Contreras-García, Itzel Jatziri, Sánchez-Huerta, Karla, Queiroz, Claudio M. T., Gallardo Gudiño, Luis Ricardo, Mendoza-Torreblanca, Julieta G., Zamudio, Sergio R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565946/
https://www.ncbi.nlm.nih.gov/pubmed/32933015
http://dx.doi.org/10.3390/brainsci10090634