Cargando…
Levetiracetam Reduced the Basal Excitability of the Dentate Gyrus without Restoring Impaired Synaptic Plasticity in Rats with Temporal Lobe Epilepsy
Temporal lobe epilepsy (TLE), the most common type of focal epilepsy, affects learning and memory; these effects are thought to emerge from changes in synaptic plasticity. Levetiracetam (LEV) is a widely used antiepileptic drug that is also associated with the reversal of cognitive dysfunction. The...
Autores principales: | González-H, Guillermo, Contreras-García, Itzel Jatziri, Sánchez-Huerta, Karla, Queiroz, Claudio M. T., Gallardo Gudiño, Luis Ricardo, Mendoza-Torreblanca, Julieta G., Zamudio, Sergio R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7565946/ https://www.ncbi.nlm.nih.gov/pubmed/32933015 http://dx.doi.org/10.3390/brainsci10090634 |
Ejemplares similares
-
Synaptic Vesicle Protein 2A Expression in Glutamatergic Terminals Is Associated with the Response to Levetiracetam Treatment
por: Contreras-García, Itzel Jatziri, et al.
Publicado: (2021) -
Levetiracetam Mechanisms of Action: From Molecules to Systems
por: Contreras-García, Itzel Jatziri, et al.
Publicado: (2022) -
The Dentate Gyrus and Temporal Lobe Epilepsy: An “Exciting”
Era
por: Scharfman, Helen E.
Publicado: (2019) -
Evaluation of the Antioxidant Activity of Levetiracetam in a Temporal Lobe Epilepsy Model
por: Ignacio-Mejía, Iván, et al.
Publicado: (2023) -
Exciting times for inhibition: GABAergic synaptic transmission in dentate gyrus interneuron networks
por: Ramaswamy, Srikanth
Publicado: (2015)