RASSF1A Suppresses Estrogen-Dependent Breast Cancer Cell Growth through Inhibition of the Yes-Associated Protein 1 (YAP1), Inhibition of the Forkhead Box Protein M1 (FOXM1), and Activation of Forkhead Box Transcription Factor 3A (FOXO3A)

SIMPLE SUMMARY: The majority of breast cancers express the estrogen receptor alpha (ERα). This receptor is of central importance for breast cancer development and tumor outgrowth, and represents an important target for therapeutic intervention. However, the molecular mechanisms that are responsible...

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Detalles Bibliográficos
Autores principales: Roßwag, Sven, Thiede, Gitta, Sleeman, Jonathan P., Thaler, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566002/
https://www.ncbi.nlm.nih.gov/pubmed/32967092
http://dx.doi.org/10.3390/cancers12092689

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