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Disseminated histoplasmosis in a kidney liver transplant patient from a non-endemic area: A diagnostic challenge

Disseminated histoplasmosis is a rare opportunistic infection in non-endemic areas, where the disease is often diagnosed late. The spectrum of clinical manifestations is broad and life-threatening complications occur. We present a detailed case of a kidney liver transplant patient with disseminated...

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Autores principales: Carmans, L., Van Craenenbroeck, A., Lagrou, K., Deroose, C.M., Sagaert, X., Wolthuis, A., Van Wijngaerden, E., Kuypers, D.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566087/
https://www.ncbi.nlm.nih.gov/pubmed/33088713
http://dx.doi.org/10.1016/j.idcr.2020.e00971
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author Carmans, L.
Van Craenenbroeck, A.
Lagrou, K.
Deroose, C.M.
Sagaert, X.
Wolthuis, A.
Van Wijngaerden, E.
Kuypers, D.R.
author_facet Carmans, L.
Van Craenenbroeck, A.
Lagrou, K.
Deroose, C.M.
Sagaert, X.
Wolthuis, A.
Van Wijngaerden, E.
Kuypers, D.R.
author_sort Carmans, L.
collection PubMed
description Disseminated histoplasmosis is a rare opportunistic infection in non-endemic areas, where the disease is often diagnosed late. The spectrum of clinical manifestations is broad and life-threatening complications occur. We present a detailed case of a kidney liver transplant patient with disseminated histoplasmosis in a non-endemic area. Our case highlights the wide range of pathogens to consider in the immunocompromised patient, the delayed diagnosis of Histoplasmosis Capsulatum in non-endemic areas and the possibility of severe gastrointestinal disease. We also briefly review diagnostic tests and treatment options.
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spelling pubmed-75660872020-10-20 Disseminated histoplasmosis in a kidney liver transplant patient from a non-endemic area: A diagnostic challenge Carmans, L. Van Craenenbroeck, A. Lagrou, K. Deroose, C.M. Sagaert, X. Wolthuis, A. Van Wijngaerden, E. Kuypers, D.R. IDCases Case Report Disseminated histoplasmosis is a rare opportunistic infection in non-endemic areas, where the disease is often diagnosed late. The spectrum of clinical manifestations is broad and life-threatening complications occur. We present a detailed case of a kidney liver transplant patient with disseminated histoplasmosis in a non-endemic area. Our case highlights the wide range of pathogens to consider in the immunocompromised patient, the delayed diagnosis of Histoplasmosis Capsulatum in non-endemic areas and the possibility of severe gastrointestinal disease. We also briefly review diagnostic tests and treatment options. Elsevier 2020-09-28 /pmc/articles/PMC7566087/ /pubmed/33088713 http://dx.doi.org/10.1016/j.idcr.2020.e00971 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Carmans, L.
Van Craenenbroeck, A.
Lagrou, K.
Deroose, C.M.
Sagaert, X.
Wolthuis, A.
Van Wijngaerden, E.
Kuypers, D.R.
Disseminated histoplasmosis in a kidney liver transplant patient from a non-endemic area: A diagnostic challenge
title Disseminated histoplasmosis in a kidney liver transplant patient from a non-endemic area: A diagnostic challenge
title_full Disseminated histoplasmosis in a kidney liver transplant patient from a non-endemic area: A diagnostic challenge
title_fullStr Disseminated histoplasmosis in a kidney liver transplant patient from a non-endemic area: A diagnostic challenge
title_full_unstemmed Disseminated histoplasmosis in a kidney liver transplant patient from a non-endemic area: A diagnostic challenge
title_short Disseminated histoplasmosis in a kidney liver transplant patient from a non-endemic area: A diagnostic challenge
title_sort disseminated histoplasmosis in a kidney liver transplant patient from a non-endemic area: a diagnostic challenge
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566087/
https://www.ncbi.nlm.nih.gov/pubmed/33088713
http://dx.doi.org/10.1016/j.idcr.2020.e00971
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