An Aggressive Presentation of Merkel Cell Carcinoma: A Case Report

Merkel cell carcinoma (MCC) is a rare malignant neuroendocrine tumor more common in immunosuppressed old patients. It is characterized by a high frequency of local recurrence, regional nodal metastasis, distant metastasis, and low survival rate. The diagnosis of MCC is challenging due to its rarity...

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Autores principales: Ines, Zemni, Sabrine, Haddad, Saadallah, Fatma, Mohamed Ali, Ayadi, Lamia, Charfi, Riadh, Chargui, Khaled, Rahal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566174/
https://www.ncbi.nlm.nih.gov/pubmed/33047644
http://dx.doi.org/10.1177/2324709620963714
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author Ines, Zemni
Sabrine, Haddad
Saadallah, Fatma
Mohamed Ali, Ayadi
Lamia, Charfi
Riadh, Chargui
Khaled, Rahal
author_facet Ines, Zemni
Sabrine, Haddad
Saadallah, Fatma
Mohamed Ali, Ayadi
Lamia, Charfi
Riadh, Chargui
Khaled, Rahal
author_sort Ines, Zemni
collection PubMed
description Merkel cell carcinoma (MCC) is a rare malignant neuroendocrine tumor more common in immunosuppressed old patients. It is characterized by a high frequency of local recurrence, regional nodal metastasis, distant metastasis, and low survival rate. The diagnosis of MCC is challenging due to its rarity and can be clinically mistaken for other skin cancer. We report a case of locally advanced MCC of the left groin with aggressive behavior that was finally controlled with a combined treatment and we collected data from the literature to discuss the appropriate therapeutic algorithm for the management of this uncommon skin tumor.
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spelling pubmed-75661742020-10-26 An Aggressive Presentation of Merkel Cell Carcinoma: A Case Report Ines, Zemni Sabrine, Haddad Saadallah, Fatma Mohamed Ali, Ayadi Lamia, Charfi Riadh, Chargui Khaled, Rahal J Investig Med High Impact Case Rep Case Report Merkel cell carcinoma (MCC) is a rare malignant neuroendocrine tumor more common in immunosuppressed old patients. It is characterized by a high frequency of local recurrence, regional nodal metastasis, distant metastasis, and low survival rate. The diagnosis of MCC is challenging due to its rarity and can be clinically mistaken for other skin cancer. We report a case of locally advanced MCC of the left groin with aggressive behavior that was finally controlled with a combined treatment and we collected data from the literature to discuss the appropriate therapeutic algorithm for the management of this uncommon skin tumor. SAGE Publications 2020-10-13 /pmc/articles/PMC7566174/ /pubmed/33047644 http://dx.doi.org/10.1177/2324709620963714 Text en © 2020 American Federation for Medical Research https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Ines, Zemni
Sabrine, Haddad
Saadallah, Fatma
Mohamed Ali, Ayadi
Lamia, Charfi
Riadh, Chargui
Khaled, Rahal
An Aggressive Presentation of Merkel Cell Carcinoma: A Case Report
title An Aggressive Presentation of Merkel Cell Carcinoma: A Case Report
title_full An Aggressive Presentation of Merkel Cell Carcinoma: A Case Report
title_fullStr An Aggressive Presentation of Merkel Cell Carcinoma: A Case Report
title_full_unstemmed An Aggressive Presentation of Merkel Cell Carcinoma: A Case Report
title_short An Aggressive Presentation of Merkel Cell Carcinoma: A Case Report
title_sort aggressive presentation of merkel cell carcinoma: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566174/
https://www.ncbi.nlm.nih.gov/pubmed/33047644
http://dx.doi.org/10.1177/2324709620963714
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