Doege–Potter Syndrome and Hypoglycemia associated with Solitary Fibrous Tumor of the Pleura: Two Case Reports

Solitary fibrous tumors of the pleura (SFTP) are rare mesenchymal neoplasms that originate from mesenchymal growth in the pleura, tend to be single tumors, usually have an indolent course and show nonspecific symptoms. SFTP can be often diagnosed from an incidental finding of a single mass in the th...

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Autores principales: Fernández-Trujillo, Liliana, Bolaños, Jhon E, Álvarez, Carolina, Giraldo, Julián, Velásquez, Mauricio, Zúñiga-Restrepo, Valeria, Pérez, Bladimir, Sua, Luz F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566176/
https://www.ncbi.nlm.nih.gov/pubmed/33110350
http://dx.doi.org/10.1177/1179548420964759
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author Fernández-Trujillo, Liliana
Bolaños, Jhon E
Álvarez, Carolina
Giraldo, Julián
Velásquez, Mauricio
Zúñiga-Restrepo, Valeria
Pérez, Bladimir
Sua, Luz F
author_facet Fernández-Trujillo, Liliana
Bolaños, Jhon E
Álvarez, Carolina
Giraldo, Julián
Velásquez, Mauricio
Zúñiga-Restrepo, Valeria
Pérez, Bladimir
Sua, Luz F
author_sort Fernández-Trujillo, Liliana
collection PubMed
description Solitary fibrous tumors of the pleura (SFTP) are rare mesenchymal neoplasms that originate from mesenchymal growth in the pleura, tend to be single tumors, usually have an indolent course and show nonspecific symptoms. SFTP can be often diagnosed from an incidental finding of a single mass in the thorax and should be confirmed by biopsy and immunohistochemistry. A minority of cases may present Doege–Potter syndrome (DPS, episodes of refractory hypoglycemia) associated with production of insulin-like growth factor 2 (IGF-2). Both SFTP and DPS are rare occurrences with less than 2000 cases reported worldwide. The curative treatment is tumor resection. Two cases of patients with DPS caused by SFTP are presented below.
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spelling pubmed-75661762020-10-26 Doege–Potter Syndrome and Hypoglycemia associated with Solitary Fibrous Tumor of the Pleura: Two Case Reports Fernández-Trujillo, Liliana Bolaños, Jhon E Álvarez, Carolina Giraldo, Julián Velásquez, Mauricio Zúñiga-Restrepo, Valeria Pérez, Bladimir Sua, Luz F Clin Med Insights Circ Respir Pulm Med Case Report Solitary fibrous tumors of the pleura (SFTP) are rare mesenchymal neoplasms that originate from mesenchymal growth in the pleura, tend to be single tumors, usually have an indolent course and show nonspecific symptoms. SFTP can be often diagnosed from an incidental finding of a single mass in the thorax and should be confirmed by biopsy and immunohistochemistry. A minority of cases may present Doege–Potter syndrome (DPS, episodes of refractory hypoglycemia) associated with production of insulin-like growth factor 2 (IGF-2). Both SFTP and DPS are rare occurrences with less than 2000 cases reported worldwide. The curative treatment is tumor resection. Two cases of patients with DPS caused by SFTP are presented below. SAGE Publications 2020-10-13 /pmc/articles/PMC7566176/ /pubmed/33110350 http://dx.doi.org/10.1177/1179548420964759 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Fernández-Trujillo, Liliana
Bolaños, Jhon E
Álvarez, Carolina
Giraldo, Julián
Velásquez, Mauricio
Zúñiga-Restrepo, Valeria
Pérez, Bladimir
Sua, Luz F
Doege–Potter Syndrome and Hypoglycemia associated with Solitary Fibrous Tumor of the Pleura: Two Case Reports
title Doege–Potter Syndrome and Hypoglycemia associated with Solitary Fibrous Tumor of the Pleura: Two Case Reports
title_full Doege–Potter Syndrome and Hypoglycemia associated with Solitary Fibrous Tumor of the Pleura: Two Case Reports
title_fullStr Doege–Potter Syndrome and Hypoglycemia associated with Solitary Fibrous Tumor of the Pleura: Two Case Reports
title_full_unstemmed Doege–Potter Syndrome and Hypoglycemia associated with Solitary Fibrous Tumor of the Pleura: Two Case Reports
title_short Doege–Potter Syndrome and Hypoglycemia associated with Solitary Fibrous Tumor of the Pleura: Two Case Reports
title_sort doege–potter syndrome and hypoglycemia associated with solitary fibrous tumor of the pleura: two case reports
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566176/
https://www.ncbi.nlm.nih.gov/pubmed/33110350
http://dx.doi.org/10.1177/1179548420964759
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