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Tetramethylpyrazine Ameliorates Lipopolysaccharide-Induced Sepsis in Rats via Protecting Blood–Brain Barrier, Impairing Inflammation and Nitrous Oxide Systems

The aim of this study was to assess the underlying impact of Tetramethylpyrazine (TMP), which is the main activity compound of Ligusticum chuanxiong Hort, on the blood–brain barrier, inflammatory and nitrous oxide systems in a rat model of lipopolysaccharide (LPS)-induced sepsis. The SD rats were di...

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Detalles Bibliográficos
Autores principales:	Huang, Zi-Sheng, Xie, Da-Qi, Xu, Li-Jun, Huang, Chang-Shun, Zheng, Min, Chen, Yi-Jun, Cao, Yin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566283/ https://www.ncbi.nlm.nih.gov/pubmed/33123008 http://dx.doi.org/10.3389/fphar.2020.562084

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