Cargando…
Novel DNA-based T-Cell Activator Promotes Rapid T-Cell Activation and Expansion
Autologous chimeric antigen receptor engineered T-cell therapies are beginning to dramatically change the outlook for patients with several hematological malignancies. Yet methods to activate and expand these cells are limited, often pose challenges to automation, and have biological limitations imp...
Autores principales: | Keskar, Vandana, Sood, Anup, Loghin, Evelina, Kovacs, Ernest, Duthie, R. Scott, Liu, Shutong, Park, Jee Hyun, Chadwick, Chrystal, Smith, Reginald, Brown, Martin, Stroncek, David F., Highfill, Steven L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566300/ https://www.ncbi.nlm.nih.gov/pubmed/32796275 http://dx.doi.org/10.1097/CJI.0000000000000329 |
Ejemplares similares
-
Point-of-care cell therapy manufacturing; it’s not for everyone
por: Stroncek, David F., et al.
Publicado: (2022) -
Single cell sequencing reveals gene expression signatures associated with bone marrow stromal cell subpopulations and time in culture
por: Liu, Shutong, et al.
Publicado: (2019) -
Large Scale Ex Vivo Expansion of γδ T cells Using Artificial Antigen-presenting Cells
por: Boucher, Justin C., et al.
Publicado: (2023) -
T cell receptor dynamic and transcriptional determinants of T cell expansion in glioma-infiltrating T cells
por: Lu, Kevin Hai-Ning, et al.
Publicado: (2022) -
Cryopreserved anti-CD22 and bispecific anti-CD19/22 CAR T cells are as effective as freshly infused cells
por: Dreyzin, Alexandra, et al.
Publicado: (2022)