Cargando…

Rosthorin A inhibits non-small cell lung cancer cell growth and metastasis through repressing epithelial-mesenchymal transition via downregulating Slug

Lung cancer always ranks first in the number of cancer deaths every year, accounting for 18.4% of total cancer deaths in 2018. Metastasis is the main cause of death in lung cancer patients. The identification of bioactive components of traditional Chinese medicine is very important for the developme...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ni, Lulu, Li, Zhongjie, Shi, Xuelin, Yao, Chao, Sun, Jiangnan, Ai, Min, Li, Shuangshuang, Liu, Yixiao, Xu, Fei, Zhou, Yuetao, Li, Jiangan, Qiu, Liying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Preclinical Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566306/ https://www.ncbi.nlm.nih.gov/pubmed/33065690 http://dx.doi.org/10.1097/CAD.0000000000000973

Ejemplares similares

Protective Effects and Mechanisms of Vaccarin on Vascular Endothelial Dysfunction in Diabetic Angiopathy
por: Xu, Fei, et al.
Publicado: (2019)

Chemical Constituents from Albiziae Cortex and Their Ability to Ameliorate Steatosis and Promote Proliferation and Anti-Oxidation In Vitro
por: Shi, Xuelin, et al.
Publicado: (2019)

Tectorigenin inhibits osteosarcoma cell migration through downregulation of matrix metalloproteinases in vitro
por: Guo, Yu, et al.
Publicado: (2016)

Antimyeloma activity of bromodomain inhibitors on the human myeloma cell line U266 by downregulation of MYCL
por: Suzuki, Kazuhito, et al.
Publicado: (2016)

Baicalin induces apoptosis in SW480 cells through downregulation of the SP1 transcription factor
por: Ma, Wenkang, et al.
Publicado: (2019)

PP242 suppresses cell proliferation, metastasis, and angiogenesis of gastric cancer through inhibition of the PI3K/AKT/mTOR pathway
por: Xing, Xiaofang, et al.
Publicado: (2014)

Vaccarin Regulates Diabetic Chronic Wound Healing through FOXP2/AGGF1 Pathways
por: Liu, Yixiao, et al.
Publicado: (2020)

Bis-anthracycline WP760 abrogates melanoma cell growth by transcription inhibition, p53 activation and IGF1R downregulation
por: Olbryt, Magdalena, et al.
Publicado: (2017)

Berberine Inhibits FOXM1 Dependent Transcriptional Regulation of POLE2 and Interferes With the Survival of Lung Adenocarcinoma
por: Ni, Lulu, et al.
Publicado: (2022)

Heart Failure With Reduced Ejection Fraction Is Characterized by Systemic NEP Downregulation
por: Pavo, Imre J., et al.
Publicado: (2020)

Surveillance of spontaneous breast cancer metastasis by TRAIL-expressing CD34(+) cells in a xenograft model
por: Rossini, Anna, et al.
Publicado: (2012)

Chlorogenic acid enhances the effects of 5-fluorouracil in human hepatocellular carcinoma cells through the inhibition of extracellular signal-regulated kinases
por: Yan, Yuan, et al.
Publicado: (2015)

Tumour suppressor EP300, a modulator of paclitaxel resistance and stemness, is downregulated in metaplastic breast cancer
por: Asaduzzaman, Muhammad, et al.
Publicado: (2017)

Slug and Vimentin downregulation at the metastatic site is associated with Skip-N2 metastasis of lung adenocarcinoma
por: Saygideger, Yasemin, et al.
Publicado: (2022)

Apoptotic and autophagic cell death induced in cervical cancer cells by a dual specific oncolytic adenovirus
por: Li, Shanzhi, et al.
Publicado: (2022)

The monoamine stabilizer (−)‐OSU6162 counteracts downregulated dopamine output in the nucleus accumbens of long‐term drinking Wistar rats
por: Feltmann, Kristin, et al.
Publicado: (2015)

CD36-mediated activation of endothelial cell apoptosis by an N-terminal recombinant fragment of thrombospondin-2 inhibits breast cancer growth and metastasis in vivo
por: Koch, Manuel, et al.
Publicado: (2010)

Intratumorally CpG immunotherapy with carbon nanotubes inhibits local tumor growth and liver metastasis by suppressing the epithelial–mesenchymal transition of colon cancer cells
por: Jin, Hongyong, et al.
Publicado: (2020)

ERα suppresses slug expression directly by transcriptional repression
por: Ye, Yin, et al.
Publicado: (2008)

VEGFA links self-renewal and metastasis by inducing Sox2 to repress miR-452, driving Slug
por: Kim, M, et al.
Publicado: (2017)

A novel gene expression signature for bone metastasis in breast carcinomas
por: Savci-Heijink, C. Dilara, et al.
Publicado: (2016)

Downregulation of miR-205 contributes to epithelial–mesenchymal transition and invasion in triple-negative breast cancer by targeting HMGB1–RAGE signaling pathway
por: Wang, Ling, et al.
Publicado: (2019)

Para-toluenesulfonamide induces tongue squamous cell carcinoma cell death through disturbing lysosomal stability
por: Liu, Zhe, et al.
Publicado: (2015)

MAGEC2, an epithelial-mesenchymal transition inducer, is associated with breast cancer metastasis
por: Yang, Fan, et al.
Publicado: (2014)

SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma
por: Luanpitpong, Sudjit, et al.
Publicado: (2015)

Evodiamine inhibits vasculogenic mimicry in HCT116 cells by suppressing hypoxia-inducible factor 1-alpha-mediated angiogenesis
por: Zeng, Di, et al.
Publicado: (2021)

MCP-1 is overexpressed in triple-negative breast cancers and drives cancer invasiveness and metastasis
por: Dutta, Pranabananda, et al.
Publicado: (2018)

Abstract 5 Human Umbilical Cord Blood-Derived Cell Therapy Product, DUOC-01, Promotes Remyelination by Driving the Differentiation of Oligodendrocyte Progenitor Cells
por: Xu, Li, et al.
Publicado: (2022)

Ad-VT enhances the sensitivity of chemotherapy-resistant lung adenocarcinoma cells to gemcitabine and paclitaxel in vitro and in vivo
por: Song, Gaojie, et al.
Publicado: (2022)

Sonodynamic Therapy Suppresses Neovascularization in Atherosclerotic Plaques via Macrophage Apoptosis-Induced Endothelial Cell Apoptosis
por: Yao, Jianting, et al.
Publicado: (2019)

LFZ-4-46, a tetrahydroisoquinoline derivative, induces apoptosis and cell cycle arrest via induction of DNA damage and activation of MAPKs pathway in cancer cells
por: Xu, Lili, et al.
Publicado: (2021)

Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis
por: Lewis Phillips, Gail D., et al.
Publicado: (2017)

Abstract 29 Umbilical Cord-derived Mesenchymal Stromal Cells Suppress Microglia Activation Induced by Demyelination
por: Xu, Li, et al.
Publicado: (2023)

Abstract 4 Umbilical Cord-Derived Mesenchymal Stromal Cells Suppress Neuroinflammation and Promote Remyelination in the Spinal Cord
por: Min, Hyunjung, et al.
Publicado: (2022)

Downregulation of miR-218 contributes to epithelial–mesenchymal transition and tumor metastasis in lung cancer by targeting Slug/ZEB2 signaling
por: Shi, Z-M, et al.
Publicado: (2017)

A Novel Mechanism for Mesenchymal Stromal Cells to Induce Long‐Term Suppression of Pulmonary Inflammation
por: Min, Hyunjung, et al.
Publicado: (2021)

FoxM1 promotes epithelial–mesenchymal transition, invasion, and migration of tongue squamous cell carcinoma cells through a c-Met/AKT-dependent positive feedback loop
por: Yang, Huiling, et al.
Publicado: (2018)

Aged Human Multipotent Mesenchymal Stromal Cells Can Be Rejuvenated by Neuron-Derived Neurotrophic Factor and Improve Heart Function After Injury
por: Song, Hui-Fang, et al.
Publicado: (2017)

A Role for Polo-Like Kinase 4 in Vascular Fibroblast Cell-Type Transition
por: Li, Jing, et al.
Publicado: (2021)

Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
por: Chien, Ming-Hsien, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_p55evho5g6h7tkokb72bb2tpm2