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TIGIT Can Exert Immunosuppressive Effects on CD8(+) T Cells by the CD155/TIGIT Signaling Pathway for Hepatocellular Carcinoma In Vitro

The efficacy of adoptive cellular immunotherapy against cancer cells is limited due to the presence of immunosuppressive cells within the solid tumor microenvironment. The upregulation of certain coinhibitory receptors may lead to exhaustion of the immune effector cells. T-cell immunoglobulin and im...

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Detalles Bibliográficos
Autores principales:	Zhang, Changkun, Wang, Yang, Xun, Xiaodong, Wang, Siqi, Xiang, Xiao, Hu, Shihua, Cheng, Qian, Guo, Jinghang, Li, Zhao, Zhu, Jiye
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Basic Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566309/ https://www.ncbi.nlm.nih.gov/pubmed/32804915 http://dx.doi.org/10.1097/CJI.0000000000000330

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